Sökning: "5 P2"
Visar resultat 16 - 20 av 53 avhandlingar innehållade orden 5 P2.
16. Design and Synthesis of Inhibitors Targeting BACE-1, an Aspartic Protease Involved in the Pathogenesis of Alzheimer’s Disease
Sammanfattning : Alzheimer’s disease (AD) is the most common form of dementia, occurring in an estimated 24 million people worldwide. Accumulation of amyloid-b peptides leads to development of plaques in the brain, which eventually stimulates hyperphosphorylation of tau proteins leading to tangles. This is believed to play a crucial role in the pathology of AD. LÄS MER
17. Elucidating Genetic and Biochemical Aspects of the P1 and Sda Carbohydrate Histo-Blood Group Antigens
Sammanfattning : Human histo-blood groups are inherited polymorphic variants that occur in the molecular structures on the humanred blood cell (RBC) surface. Introducing foreign RBCs into a recipient lacking an antigen may activate the humoraldefence leading to a hemolytic transfusion reaction. LÄS MER
18. Lateralization of human olfaction : cognitive functions and electrophysiology
Sammanfattning : In this thesis lateralization of olfactory functions was investigated by both behavioral and electrophysiological assessment, the latter with the olfactory event-related potential (OERP) technique. The olfactory sense is primarily ipsilateral in that a stimulus that is presented to one nostril is initially processed in the same hemisphere. LÄS MER
19. Visual evoked potentials in the horse
Sammanfattning : Vision is an important sense for horses, both for survival in the wild and when horses are used for work, sport or recreation. However, it is often difficult to diagnose visual impairment in this species. LÄS MER
20. Tools and annotations for variation
Sammanfattning : Since the finishing of the Human Genome Project, many next-generation (NGS) or high-throughput sequencing platforms have emerged. One of the applications of NGS technology, variant discovery, can serve as a basis for precision medicine. LÄS MER