Sökning: "5´-UTRs"

Hittade 3 avhandlingar innehållade ordet 5´-UTRs.

  1. 1. RNA-mediated virulence gene regulation in the human pathogen Listeria monocytogenes

    Författare :Edmund Loh; Jörgen Johansson; Nancy Freitag; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Listeria monocytogenes; virulence; ncRNAs; PrfA; 5´-UTRs; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : The Gram-positive human pathogen Listeria monocytogenes uses a wide range of virulence factors for its pathogenesis. The majority of its virulence genes are encoded on a 9-kb pathogenicity island and are controlled by the transcriptional activator PrfA. LÄS MER

  3. 2. Genetic and Molecular Studies of Two Hereditary Skin Disorders

    Författare :Johanna Dahlqvist; Niklas Dahl; Anders Vahlquist; Juha Kere; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Monogenic disorder; autosomal recessive congenital ichthyosis; KLICK syndrome; Ichthyin; POMP; proteasome; epidermal differentiation; Clinical genetics; Klinisk genetik; Clinical Genetics; Klinisk genetik;

    Sammanfattning : Monogenic disorders, i.e., disorders caused by mutations in a single gene, are rare and clinically heterogeneous conditions. Identification of the genetic cause of monogenic traits can bring new insights into molecular pathways and disease mechanisms. LÄS MER

  4. 3. The growth hormone receptor and growth hormone sensitivity in man

    Författare :Ruth Wickelgren; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GH sensitivity; GH receptor; quantitative RT-PCR; IGF-I; skeletal muscle; adipose tissue; tissue-specific; promoter; 5´-untranslated region; psoriasis; epidermis;

    Sammanfattning : It is well established that the response to endogenous and exogenous growth hormone (GH) varies between individuals. For example, conditions with increased catabolic rate, such as trauma, sepsis and surgery, are believed to be associated with acquired GH insensitivity. LÄS MER