Sökning: "3 p alpha"

Visar resultat 1 - 5 av 74 avhandlingar innehållade orden 3 p alpha.

1. 1. Modulation of cellular and viral functions in Epstein-Barr virus infected cells

   Författare :Marta P Imreh; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The aim of the study was to investigate the interplay of cellular and viral genes in Epstein-Barr virus (EBV) infected cells. Two aspects of this interaction have been investigated. The first aspect is related to the expression of major histocompatibility complex (MHC) class I molecules in virus infected malignant cells. LÄS MER

3. 2. The role of Notch signaling in cancer and metastasis

   Författare :Anders P Mutvei; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The Notch signaling pathway is an evolutionary conserved cell-to-cell communication pathway that regulates many important aspects in the development and tissue homeostasis of multicellular animals. It operates in a wide range of cellular contexts and dysregulated Notch signaling has been linked to a number of diseases, including cancer. LÄS MER

4. 3. Oligodendroglial (dys)function in alpha-synucleinopathies

   Författare :Carla Azevedo; Stamcellslaboratoriet för sjukdomsmodellering i det centrala nervsystemet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Synucleinopathies; iPSCs; oligodendrocytes; alpha-synuclein; HLA; cell maturation; immunoproteasome;

   Sammanfattning : The complexity of a-synucleinopathies, which include multiple system atrophy (MSA) and Parkinson’s disease (PD), is not entirely understood. It is known that pathological accumulation of a-synuclein (a-syn) into proteinaceous aggregates is a cellular hallmark of these diseases. LÄS MER

5. 4. Reaction Cross Section Measurements for p,d,3He and 4He at Intermediate Energies

   Författare :Agris Auce; Bo Höistad; Anders Ingemarsson; Florin Carstoiu; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nuclear physics; Reaction cross section; proton; deuteron; 3He; alpha particle; measurement; intermediate energy; Kärnfysik; Nuclear physics; Kärnfysik;

   Sammanfattning : Reaction cross sections were measured for protons at 65.5 MeV, for deuterons at 37.8, 65.5, 97. LÄS MER

7. 5. Alpha-1-antitrypsin deficiency (PiZ): Clinical studies with special regard to hepatic and vasculitic disorders

   Författare :Abdul-Nasser Elzouki; Malmö Institutionen för kliniska vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gastro-enterology; systemic vasculitis; small-vessel vasculitis; serpins; genetic hemochromatosis; chronic hepatitis C; chronic liver disease; Alpha-1-antitrypsin deficiency; alpha-1-antichymotrypsin deficiency; Gastroenterologi; Urology; nephrology; Urologi; nefrologi;

   Sammanfattning : Homozygous alpha-1-antitrypsin (AAT)deficiency (PiZZ) is known to predispose to emphysema and chronic liver disease (CLD). The overall aim of the studies upon which this thesis is based was to investigate extra-pulmonary disease manifestations of AAT deficiency with special reference to hepatic and vasculitic disorders. LÄS MER