Sökning: "3′-dithiobisindoles"

Hittade 1 avhandling innehållade ordet 3′-dithiobisindoles.

1. 1. Application of metalation reactions for synthesis of sulfur/selenium-containing heterocyclic compounds

   Författare :Hamid Shirani; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Heterocycles; indoles; 3- arylthio indoles; thiopyranobisindoles; dibenzothiepins; 3; 3′-dithiobisindoles; alkaloids; echinosulfone A; cyclization; ortho-metalation; McMurry coupling; sulfides; sulfones and disulfides;

   Sammanfattning : This thesis deals mainly with the synthesis of various sulfur/selenium-containing heterocyclic compounds, many of which include structural features present in several biologically active molecules, with particular emphasis on compounds of synthetic importance, such as indoles, as well as other heteroaromatic species. In the first part, an efficient procedure toward synthesis of new 3-(arylthio)indoles based on reactions of aryl Grignard reagents or lithiated heteroaromatics with protected 3,3′-dithiobisindoles is described. LÄS MER