Sökning: "3’ untranslated region"

Visar resultat 1 - 5 av 40 avhandlingar innehållade orden 3’ untranslated region.

1. 1. On the Regulation of Ornithine Decarboxylase

   Författare :Eva Lövkvist Wallström; Institutionen för experimentell medicinsk vetenskap; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Fysiologi; Physiology; Crithidia fasciculata.; polyamines; Ornithine decarboxylase; translational control; osmolarity; untranslated region; COS cells; CHO cells; transfection; protein turnover; PEST region;

   Sammanfattning : The polyamines putrescine, spermidine and spermine have been shown to be involved in cell growth and differentiation, and are considered to be crucial components of the living cell. The synthesis of polyamines in the cell is strictly regulated. LÄS MER

3. 2. Role of the 3'UTR in translation and stability of HCV and HPV mRNAs

   Författare :Lisa Wiklund; Laszlo Szekely; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Hepatitis C virus; Human Papillomavirus; 3’ untranslated region; AU-rich sequence; mRNA stability; translation; Biokemi; Biochemistry; Biokemi; Medical Virology; medicinsk virologi;

   Sammanfattning : Virus mRNAs can be divided into functional regions. The focus of this thesis will be to investigate the function of one of these regions, the 3’ untranslated region (UTR). The 3’UTR of HCV contains a U-rich element and the late 3’UTR of HPV-1 contains an AU-rich element. LÄS MER

4. 3. The growth hormone receptor and growth hormone sensitivity in man

   Författare :Ruth Wickelgren; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GH sensitivity; GH receptor; quantitative RT-PCR; IGF-I; skeletal muscle; adipose tissue; tissue-specific; promoter; 5´-untranslated region; psoriasis; epidermis;

   Sammanfattning : It is well established that the response to endogenous and exogenous growth hormone (GH) varies between individuals. For example, conditions with increased catabolic rate, such as trauma, sepsis and surgery, are believed to be associated with acquired GH insensitivity. LÄS MER

5. 4. Receptors for growth hormone and prolactin. Regulation and activation

   Författare :Gunnel Hellgren; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Growth hormone; GH receptor; Janus kinase; GH sensitivity; 5 -untranslated region; prolactin; prolactin receptor adipose tissue; liver; skeletal muscle; epidermal growth factor receptor; tyrosine kinase; kinase activity;

   Sammanfattning : Cytokine receptor activation is dependent on ligand-induced receptor dimerization or oligomerization and subsequent activation of several intracellular proteins. Activation of Janus kinases (Jaks) is probably the first intracellular event that occurs after receptor dimerization. LÄS MER

7. 5. Control of human papillomavirus type 1 late mRNA stability and translation by an AU-rich RNA element

   Författare :Marcus Sokolowski; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; HPV-1; HPV-16; late genes; 3´ UTR; L1; L2; c-fos; AU rich element; HuR; hnRNP C1 C2; mRNA stability; translation; Biokemi; Biochemistry; Biokemi; Medical Virology; medicinsk virologi;

   Sammanfattning : Human Papillomaviruses (HPVs) infect the epithelial tissues in humans and infection with certain high-risk types is associated with cancer. The expressionof the HPV late capsid genes is dependent on cell differentiation. This may be one reason for the lack of HPV replication in vitro. LÄS MER