Sökning: "2D-gel"

Visar resultat 1 - 5 av 12 avhandlingar innehållade ordet 2D-gel.

  1. 1. Statistical and Functional Analysis of Genomic and Proteomic Data

    Författare :Yingchun Liu; Beräkningsbiologi och biologisk fysik - Genomgår omorganisation; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bioinformatik; biomathematics biometrics; unsupervised classification; Bioinformatics; medical informatics; TGF-beta; linear mixed model; expression data; dye bias; 2D-gel; signaling pathway; regulatory motif; microarray; medicinsk informatik; biomatematik;

    Sammanfattning : High-throughput technologies have led to an explosion in the availability of data at the genome scale. Such data provide important information about cellular processes and causes of human diseases, as well as for drug discovery. Deciphering the biologically relevant results from these data requires comprehensive analytical methods. LÄS MER

  3. 2. Stress response in the cyanobacterium Synechocystis sp. PCC 6803

    Författare :Helder Miranda; Christiane Funk; Hans-Erik Åkerlund; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cyanobacteria; High light; heat stress; ROS; Photosynthesis; Photosystem II; Deg HtrA proteases; small CAB-like proteins; Refraction-2D™; MALDI-TOF; 2D-gel; GC-MS; PCA; OPLS-DA; EPS; S-layer; Biochemistry; Biokemi; biokemi; Biochemistry;

    Sammanfattning : Adaptation to environmental changes is important for the survival of living organisms. Under extreme abiotic conditions, organic molecules (such as lipids, proteins and nucleic acids) are prone to damage. LÄS MER

  4. 3. Effects of polyamine pool manipulation on genes expressed during the cell cycle

    Författare :Pia Berntsson; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Animal physiology; cyclin A; ODC; MCF-7; mitotic shake off; DENSPM; CHO; cDNA microarray; cell cycle; spermine; Djurfysiologi; AdoMetDC; 2D gel electrophoresis; polyamines; spermidine; putrescine;

    Sammanfattning : The polyamines - putrescine, spermidine and spermine - are polycations found within cells. They have been shown to be essential for optimal cell proliferation and cell survival. Cells maintain their polyamine levels in a well-regulated system involving biosynthesis, catabolism and uptake/excretion. LÄS MER

  5. 4. Glucocorticoid receptor function : interactions, mutants and ligand responses

    Författare :Erik Hedman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Glucocorticoid receptor; glucocorticoids; cross-talk; GR interacting proteins; Flt3; mass spectrometry; 2D gel electrophoresis;

    Sammanfattning : The protein that is investigated in this thesis is the glucocorticoid receptor (GR), which belongs to the nuclear hormone receptor superfamily of ligand activated transcription factors. The nuclear receptors share three conserved structural domains, the N-terminal transactivating domain, the central DNA-binding domain and the C-terminal ligand-binding domain. LÄS MER

  7. 5. Sample preparation and mass spectrometry in proteome studies

    Författare :Daniel Hirschberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Proteome studies aim to link gene to function. Instead of screening for function in a specific protein as in classical protein chemistry, proteins are now screened against a specific phenotype, disease or metabolic state. LÄS MER