Sökning: "2023"

Visar resultat 1 - 5 av 3312 avhandlingar innehållade ordet 2023.

1. 1. Proteomic strategies for blood biomarker development in rare dystrophinopathies

   Författare :Camilla Johansson; Cristina Al-Khalili Szigyarto; Ola Söderberg; KTH; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Duchenne muscular dystrophy; Becker muscular dystrophy; proteomics; affinity-proteomics; biomarkers; DIA-MS; SRM-MS; immunoassay; suspension bead arrays; Duchenne muskeldystrofi; Becker muskeldystrofi; proteomik; affinitetsproteomik; biomarkörer; DIA-MS; SRM-MS; immunoassay; suspension bead array; Biotechnology; Bioteknologi;

   Sammanfattning : Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are two rare genetic disorders of the family dystrophinopathy. They are both caused by the lack of, or reduced production of, the protein dystrophin. LÄS MER

3. 2. Centrifugal microfluidics-based point of care diagnostics at resource limited settings

   Författare :Ahmad Saleem Akhtar; Aman Russom; Ines Fernandes Pinto; Nicole Pamme; KTH; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microfluidics; centrifugal microfluidics; point-of-care; low-cost; diagnostics; agarose beads; immunoassays; colorimetry; fluorescence; cytokines; nucleic acid amplification; isothermal amplification; COVID-19; portable; smartphone; resource limited settings.; Biotechnology; Bioteknologi;

   Sammanfattning : Advancements in medical diagnostics have allowed us to understand the underlying mechanism and treat the root cause for many diseases which had been causing morbidity and mortality up until this point in human history. Furthermore, many of the standard diagnostic procedures have now been transformed to provide answers at or near the point-of-care. LÄS MER

4. 3. Development and application of spatial transcriptomics methods

   Författare :Zaneta Andrusivova; Joakim Lundeberg; Jay W. Shin; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; RNA; Spatial Transcriptomics; RNA sequencing; Biotechnology; Bioteknologi;

   Sammanfattning : Transcriptomics is one of the pivotal fields in molecular biology, enabling comprehensive analysis of gene expression patterns. Recent advancements in the biotechnology field have transformed the transcriptomics research, providing insights into the complexity of cellular processes in a greater detail. LÄS MER

5. 4. Synthesis, Electrophoretic Deposition, and Characterization of Nanostructured Thermoelectric Materials

   Författare :Hazal Batili; Muhammet Toprak; Oliver Fenwick; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Thermoelectric; Bismuth telluride; Antimony telluride; Hydrothermal synthesis; Thermolysis; Polyol; Electrophoretic deposition; EPD; Seebeck coefficient; Thermoelectric power factor; Colloidal stabilization; Material and Nano Physics; Material- och nanofysik;

   Sammanfattning : The world’s increasing demand for energy and supplying this energy dominantlyfrom fossil fuels has a major impact on global climate change. Theenergy crisis has gotten more alarming in the recent years which increasedthe motivation for replacing fossil fuels with greener routes for energy harvest. LÄS MER

7. 5. Autoantibody profiling in autoimmune diseases

   Författare :Shaghayegh Bayati; Peter Nilsson; Elisa Pin; Peter Heeringa; KTH; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Autoimmunity; Autoantibodies; Vasculitis; Systemic Sclerosis; affinity proteomics; Biotechnology; Bioteknologi;

   Sammanfattning : Autoimmune disease diagnosis and definition of prognosis can be challenging. Patients with the same autoimmune disease could present with very heterogeneous symptoms. Therefore, there is a need to understand the disease better to improve patients’ diagnosis, and classification, and tailor the treatment. LÄS MER