Sökning: "2-O-sulfotransferase"

Hittade 3 avhandlingar innehållade ordet 2-O-sulfotransferase.

  1. 1. In Vitro Studies of the Substrate Specificities of Heparan Sulfate 2-O- and 6-O-sulfotransferases

    Författare :Emanuel Smeds; Marion Kusche-Gullberg; Ulf Lindahl; Catherine L. R. Merry; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; heparan sulfate; heparin; sulfotransferase; 2-O-sulfotransferase; 6-O-sulfotransferase; polysaccharide biosynthesis; glycosaminoglycan; O-sulfotransferase; proteoglycan; Biokemi; Biochemistry; Biokemi;

    Sammanfattning : Heparan sulfate (HS), a linear negatively charged polysaccharide located at the cell surface and in the extracellular matrix, interacts with, and thereby regulates the functions of numerous proteins. HS-protein interactions depend on the fine structure of HS, especially its sulfation pattern. LÄS MER

  3. 2. Understanding Heparan Sulfate Biosynthesis and Functional Implications of Heparanase

    Författare :Tianyi Song; Dorothe Spillmann; Cathrine Merry; Uppsala universitet; []
    Nyckelord :Heparan sulfate; biosynthesis; heparanase; lipid metabolism; cancer; cell adhesion; apoptosis.; Molekylär medicin;

    Sammanfattning : Heparan sulfate (HS) proteoglycans are present on the plasma membrane of all animal cells studied so far and are a major component of extracellular matrices. Heparanase is an endo-ß-glucuronidase that cleaves HS chains at internally located ß-glucuronidic linkages1. LÄS MER

  4. 3. Formation of Iduronic Acid during Chondroitin/Dermatan Sulfate Biosynthesis

    Författare :Emil Tykesson; Lungbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GLYCOSAMINOGLYCAN; CHONDROITIN; DERMATAN; EPIMERASE; SULFOTRANSFERASE; GLYCOSAMINOGLYCAN; CHONDROITIN SULFATE; DERMATAN SULFATE; EPIMERASE; SULFOTRANSFERASE;

    Sammanfattning : All animals and some bacteria can synthesize linear polysaccharides with a backbone of repeating disaccharideunits, called glycosaminoglycans (GAGs). The GAGs are either attached to a protein core, as in proteoglycans (PGs), or exist as free polymer chains, as in hyaluronan. LÄS MER