Sökning: "13C natural-abundance solid-state NMR"

Hittade 2 avhandlingar innehållade orden 13C natural-abundance solid-state NMR.

  1. 1. Skin hydration - How water and osmolytes influence biophysical properties of stratum corneum

    Författare :Sebastian Björklund; Fysikalisk kemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Stratum corneum; diffusive transport; permeability; flow-through cell; Franz cell; transdermal drug delivery; water activity; vapor pressure; osmotic gradient; relative humidity; ceramide; free fatty acid; cholesterol; keratin filaments; natural moisturizing factor NMF ; urea; glycerol; molecular mobility; 13C natural-abundance solid-state NMR; polarization transfer; isothermal calorimetry; impedance spectroscopy; X-ray diffraction;

    Sammanfattning : The outermost layer of skin (i.e., the stratum corneum, SC) is the interface that separates the water-rich inside of the body from the relatively dry external environment. SC forms an effective permeability barrier, which has to be overcome in transdermal drug delivery. LÄS MER

  3. 2. Structure and Dynamics in Amphiphilic Bilayers: NMR and MD simulation Studies

    Författare :Tiago Ferreira; Fysikalisk kemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Solid-state nuclear magnetic resonance (NMR) spectroscopy and molecular dynamics (MD) simulations were employed to study molecular structure and dynamics in amphiphilic bilayers. This thesis reports on method development and practical applications to two types of bilayer systems: simple cell membrane models composed of phosphatidylcholine lipids and cholesterol; and liquid crystals composed of ethyleneoxide-based surfactants often used in technological applications and in fundamental studies of amphiphile self-assembly. LÄS MER