Sökning: "1255"

Visar resultat 1 - 5 av 29 avhandlingar innehållade ordet 1255.

1. 1. Azoles and Contaminants in Treated Effluents Interact with CYP1 and CYP19 in Fish

   Författare :Kristina Beijer; Ingvar Brandt; Björn Brunström; Henner Hollert; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Azole; fungicide; chemical; CYP1A; CYP19; EROD; aromatase; effluent; STP; wastewater; fish; stickleback; rainbow trout; Biologi med inriktning mot ekotoxikologi; Biology with specialization in Environmental Toxicology;

   Sammanfattning : Numerous contaminants are present in mixtures in the aquatic environment. Among these are the azoles, a group of chemicals that includes both pharmaceuticals and pesticides. Azole fungicides are designed to inhibit lanosterol 14-demethylase (cytochrome P450 (CYP) 51), while other azoles are intended to inhibit aromatase (CYP19), i.e. LÄS MER

3. 2. Clinical, epidemiological and immunological aspects of Lyme borreliosis with special focus on the role of the complement system

   Författare :Anna J Henningsson; Jan Ernerudh; Pia Forsberg; Kristina Nilsson Ekdahl; Bo-Eric Malmvall; Lars Hagberg; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lyme borreliosis; neuroborreliosis; clinical; epidemiology; inflammation; complement; cytokine; chemokine;

   Sammanfattning : Lyme borreliosis (LB) is the most common vector-borne disease in the Northern Hemisphere. The infection is caused by spirochetes belonging to the Borrelia burgdorferi sensu lato complex, and it is transmitted to humans by ticks. LÄS MER

4. 3. Chlamydia trachomatis as a risk factor for infertility in women and men, and ovarian tumor development

   Författare :Annika Idahl; Ulrika Ottander; Jan I Olofsson; Eva Lundin; Fredrik Elgh; Jorma Paavonen; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antibodies; borderline tumors; Chlamydia trachomatis; cHSP60; DNA; infertility; ovarian cancer; pregnancy rate; RNA; semen characteristics; Obstetrics and gynaecology; Obstetrik och gynekologi; obstetrik och gynekologi; Obstetrics and Gynaecology;

   Sammanfattning : Background: Chlamydia trachomatis in women is a risk factor for tubal factor infertility and extra uterine pregnancies, but the impact of a C. trachomatis infection on male fertility is unclear. It is also hypothesized that persistent infection with C. trachomatis, or other microorganisms, might initiate/promote ovarian tumor development. LÄS MER

5. 4. Studies in Estimation of Patterned Covariance Matrices

   Författare :Martin Ohlson; Timo Koski; Dietrich von Rosen; Augustyn Markiewicz; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MATHEMATICS; MATEMATIK;

   Sammanfattning : Many testing, estimation and confidence interval procedures discussed in the multivariate statistical literature are based on the assumption that the observation vectors are independent and normally distributed. The main reason for this is that often sets of multivariate observations are, at least approximately, normally distributed. LÄS MER

7. 5. Diabetes mellitus and related glucometabolic disturbances in acute myocardial infarction : Diagnosis, prevalence and prognostic implications

   Författare :Åke Tenerz; Jerzy Leppert; Christian Berne; Klas Malmberg; Göran Nilsson; Johan Herlitz; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Diabetes mellitus; impaired glucose tolerance; insulin resistance; prevalence; diagnosis; oral glucose tolerance test; acute myocardial infarction; prognosis; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; Medicine; medicin;

   Sammanfattning : In patients with diabetes mellitus (DM), acute myocardial infarction (AMI) is a major cause of death. We have studied two populations with respect to the relationship between DM or related glucometabolic disturbances and AMI. LÄS MER