Sökning: "11C-vorozole"
Hittade 2 avhandlingar innehållade ordet 11C-vorozole.
1. Regulation of Ovarian Aromatase: Studies by Aromatase Assays in vitro and in vivo
Sammanfattning : An in vitro method was developed for measuring aromatase, based on binding of competitive aromatase inhibitor [11C]vorozole to the active site of the enzyme. [11C]Vorozole displayed high, specific binding in vitro to human placenta and human granulosa cells (GC), both fresh and frozen/thawed cells, provided correct procedures were used. LÄS MER
2. Imaging brain aromatase by using PET : A way to study anabolic steroid abuse
Sammanfattning : Aromatase is an enzyme that facilitates the conversion of androgens to estrogens and may play a role in mood and mental status. The main theme of this thesis is the imaging of brain aromatase by use of the PET technique. The PET tracer for aromatase, 11C-labeled vorozole (VOZ) was developed and evaluated by with in vitro and in vivo methods. LÄS MER