Sökning: "γδ T cells"

Visar resultat 6 - 10 av 24 avhandlingar innehållade orden γδ T cells.

  1. 6. T cells in colon cancer; migration and effector functions

    Författare :Louis Szeponik; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Treg; CRC; TIL; nSMase2; Transendothelial migration; Unconventional T cells;

    Sammanfattning : Immune cells are recognised as one of the main players in the tumor microenvironment and targeted by many new cancer therapies. Regulatory T cells (Treg) can suppress tumor infiltrating lymphocytes which are associated with a better patient outcome. LÄS MER

  3. 7. Butyrophilin- and Butyrophilin-like genes and their role in epithelial cell-intraepithelial T lymphocyte cross-talk

    Författare :Cristina Lebrero-Fernandez; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Butyrophilin-like Btnl ; Butyrophilin Btn ; Intraepithelial lymphocytes IELs ; Mucosal immunity; Intestinal epithelial cells; γδ T cells; Intestinal inflammation; Colon cancer; Ulcerative colitis;

    Sammanfattning : More than 50% of our immune system is located in the gut. The intestinal epithelium, which forms an interface between the organism and the environment, harbors intraepithelial lymphocytes (IELs) that comprise a mixture of conventional αβ T cells and unconventional αβ- and γδ T cells. LÄS MER

  4. 8. Cutaneous resistance against Francisella tularensis

    Författare :Stephan Stenmark; Mikael Rhen; Umeå universitet; []
    Nyckelord :tularemia; Francisella tularensis; skin; protection; cytokines; T-cells; B-cells; specific antibodies; Infectious Diseases; infektionssjukdomar;

    Sammanfattning : Francisella tularensis, the causative agent of tularemia, is a potent pathogen in humans and other mammals. The ulceroglandular form of the disease is the most common expression in humans with a clinical picture characterized by a skin ulcer, enlarged regional lymph nodes and fever. LÄS MER

  5. 9. Immune maturation and lymphocyte characteristics in relation to early gut bacteria exposure

    Författare :Sophia Björkander; Eva Sverremark Ekström; Hanne Frøkiær; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Allergy; cell-free supernatant; chemokines; colonization; cytokines; FOXP3; immune-maturation; lactobacilli; lymphocytes; NK-cells; Staphylococcus aureus; unconventional T-cells; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : At birth, the immune system is immature and the gut microbiota influences immune maturation. Staphylococcus aureus (S. aureus) and lactobacilli are part of the neonatal gut microbiota and have seemingly opposite effects on the immune system. S. LÄS MER

  7. 10. Expansion of circulatory Vγ9Vδ2 T cells in tularemia and Pontiac fever, two intracellular bacterial diseases with widely different clinical expression

    Författare :Michal Kroca; Dieter Kabelitz; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Francisella tularensis; Gamma-delta T cell; Legionella; Legionellosis; Lymphocyte; T cell Tularemia; Immunologi; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : Although well established that human Vγ9Vδ2 T cells may expand in circulation during intracellular bacterial infections, most underlying studies included only a few cases and only some diseases had been studied so far. In tularemia, a severe invasive disease, only one patient had been described. LÄS MER