Sökning: "β-catenin"
Visar resultat 21 - 25 av 73 avhandlingar innehållade ordet β-catenin.
21. Targeting dysfunctional developmental signaling cascades as a tool for tailored therapy in embryonal tumors
Sammanfattning : Neuroblastoma and medulloblastoma are embryonal malignant tumors of the central and peripheral nervous systems, respectively. The overall survival for both diagnoses is 60-75% despite intense multimodal therapy. This warrants the search for novel therapeutic approaches. LÄS MER
22. Wnt signaling affects cell adhesion and neuronal differentiation
Sammanfattning : The mammalian central nervous system (CNS) consists of the brain and the spinal cord. The entire CNS is derived from the walls of a fluid-filled neural tube that is formed at an early stage of embryonic development. The tube itself becomes the adult ventricular system. LÄS MER
23. Squamous cell carcinoma of the oral tongue : studies of biomarkers connected to human papillomavirus infection, epithelial to mesenchymal transition and locoregional metastatis
Sammanfattning : Background: Oral Tongue Squamous Cell Carcinoma (OTSCC) is the most frequent and aggressive carcinoma in the head and neck region. Its incidence has increased during the last decades, especially in young patients (≤40 years) mainly female. LÄS MER
24. The impact of Wnt5a signaling and tumor associated macrophages in breast cancer
Sammanfattning : Breast cancer is the most common cancer among women worldwide with approximately 1.150.000 new cases each year and accounting for over 400.000 deaths per year. LÄS MER
25. The Role of Inflammatory Lipid Mediators on Colon Cancer Initiating Cells (CICs)
Sammanfattning : Colorectal cancer (CRC) is one of the major causes of cancer globally. Recent studies proposed a role for cancer initiating cells (CICs), a small subset of replication-competent cells, in colon carcinogenesis. LÄS MER