Sökning: "β-catenin"

Visar resultat 21 - 25 av 73 avhandlingar innehållade ordet β-catenin.

  1. 21. Targeting dysfunctional developmental signaling cascades as a tool for tailored therapy in embryonal tumors

    Författare :Cecilia Dyberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Neuroblastoma and medulloblastoma are embryonal malignant tumors of the central and peripheral nervous systems, respectively. The overall survival for both diagnoses is 60-75% despite intense multimodal therapy. This warrants the search for novel therapeutic approaches. LÄS MER

  3. 22. Wnt signaling affects cell adhesion and neuronal differentiation

    Författare :Maria Lindqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The mammalian central nervous system (CNS) consists of the brain and the spinal cord. The entire CNS is derived from the walls of a fluid-filled neural tube that is formed at an early stage of embryonic development. The tube itself becomes the adult ventricular system. LÄS MER

  4. 23. Squamous cell carcinoma of the oral tongue : studies of biomarkers connected to human papillomavirus infection, epithelial to mesenchymal transition and locoregional metastatis

    Författare :Nicola Sgaramella; Karin Nylander; Karin Danielsson; Giuseppe Colella; Robin Fåhraeus; Lorenzo Lo Muzio; George Sekine; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; squamous cell carcinoma oral tongue; p16; HPV; podoplanin; E-cadherin; patologi; Pathology;

    Sammanfattning : Background: Oral Tongue Squamous Cell Carcinoma (OTSCC) is the most frequent and aggressive carcinoma in the head and neck region. Its incidence has increased during the last decades, especially in young patients (≤40 years) mainly female. LÄS MER

  5. 24. The impact of Wnt5a signaling and tumor associated macrophages in breast cancer

    Författare :Catharina Hagerling; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; Wnt5a; E-cadherin; B-catenin; migration; invasion; turnor associated macrophages; CD163; CD68; turnor stroma;

    Sammanfattning : Breast cancer is the most common cancer among women worldwide with approximately 1.150.000 new cases each year and accounting for over 400.000 deaths per year. LÄS MER

  7. 25. The Role of Inflammatory Lipid Mediators on Colon Cancer Initiating Cells (CICs)

    Författare :Kishan Bellamkonda; Malmö Cellpatologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Colorectal cancer (CRC) is one of the major causes of cancer globally. Recent studies proposed a role for cancer initiating cells (CICs), a small subset of replication-competent cells, in colon carcinogenesis. LÄS MER