Sökning: "αDC1"

Hittade 1 avhandling innehållade ordet αDC1.

1. 1. Dendritic cells in cancer immunotherapy

   Författare :Karin Gustafsson; Göteborgs universitet; []
   Nyckelord :vaccines; dendritic cells; αDC1; PGE2DC; natural killer cells; T cells;

   Sammanfattning : Dendritic cells (DCs) play a central role in the initiation and regulation of innate and adaptive immune responses and have increasingly been applied as vaccines for cancer patients. Ex vivo generation and antigen loading of monocyte-derived DCs allows a controlled maturation, with the aim of imprinting different DC functions that are essential for their subsequent induction of a T cell-mediated anti-tumor response. LÄS MER