Sökning: "α2-adrenoceptors"

Hittade 4 avhandlingar innehållade ordet α2-adrenoceptors.

  1. 1. α1- and α2-Adrenoceptors in the Eye : Pharmacological and Functional Characterization

    Författare :Anna Wikberg-Matsson; Thomas Mittag; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; α1-adrenoceptor subtypes; α2-adrenoceptor subtypes; iris; ciliary body; choroid; retina; ciliary artery; Neurovetenskap; Neurology; Neurologi; Ophtalmology; oftalmiatrik;

    Sammanfattning : α1- and α2-Adrenoceptors are involved in various physiological events in the eye: blood flow regulation, aqueous humor dynamics and pupil regulation. The α1- and α2-adrenoceptors can be further subdivided into six subtypes (α1A, α1B, α1D, α2A , α2B, and α2C ). LÄS MER

  3. 2. Discovery of N-hydroxyguanidines as novel electron acceptors of xanthine oxidase : Potential new drugs for treatment of ischemia and reperfusion injury

    Författare :Maija Dambrova; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; xanthine oxidase; N-hydroxyguanidine derivatives; ischemia and reperfusion; reduction; inhibition; superoxide; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; galenisk farmaci; Pharmaceutics;

    Sammanfattning : Xanthine oxidase (EC 1.1.3.22) is one of the major enzymatic sources of oxygen-derived free radicals. LÄS MER

  4. 3. Mode of action of asenapine vs. other antipsychotic drugs : an experimental analysis

    Författare :Olivia Frånberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Antipsychotic drugs (APDs) are used in the treatment of schizophrenia and manic or mixed episodes associated with bipolar I disorder. Generally, the so-called atypical APDs, such as clozapine, may in contrast to typical APDs improve not only positive, but also negative symptoms and some aspects of cognitive impairment associated with schizophrenia. LÄS MER

  5. 4. Novel pharmacological treatment alternatives for schizophrenia

    Författare :Charlotte Wiker; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Antipsychotic drugs are commonly divided into typical (first generation) and atypical (second generation) antipsychotic drugs. Clinically effective doses of typical antipsychotic drugs generate a striatal dopamine D2 receptor occupancy of about 70 80%, approaching a level that is associated with a high risk of extrapyramidal side effects. LÄS MER