Sökning: "α-ketoglutarate dehydrogenase"

Hittade 4 avhandlingar innehållade orden α-ketoglutarate dehydrogenase.

  1. 1. Mitochondrial Energy Metabolism : Kgd4 is a novel subunit of the α-ketoglutarate dehydrogenase complex

    Författare :Manfred Heublein; Martin Ott; Flavia Fontanesi; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mitochondria; α-ketoglutarate dehydrogenase; Kgd4; Krebs cycle; Biochemistry; biokemi;

    Sammanfattning : Mitochondria are essential organelles of eukaryotic cells and are responsible for their energy metabolism. The citric acid cycle, a chain of redox reactions in the mitochondrial matrix, is a central metabolic hub. LÄS MER

  3. 2. The Role of Proline Catabolism in Candida albicans Pathogenesis

    Författare :Fitz Gerald S. Silao; Per O. Ljungdahl; Joachim Morschhäuser; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Candida albicans; proline metabolism; ATP; P5C; virulence; macrophage; hyphae; filamentation; Ras1 cAMP PKA; mitochondria; Proline dehydrogenase; P5C dehydrogenase; reactive oxygen species; Proline-P5C cycle; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Candida albicans is an opportunistic fungal pathogen that has evolved in close association with human hosts. Pathogenicity is linked to an array of virulence characteristics expressed in response to environmental cues and that reflect the requirement to take up and metabolize nutrients available in the host. LÄS MER

  4. 3. Interconnectivity of mitochondrial protein biogenesis and homeostasis

    Författare :Carmela Vázquez Calvo; Martin Ott; Jan Riemer; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mitochondria; proteostasis; protein quality control; chaperones; biokemi; Biochemistry;

    Sammanfattning : To ensure correct protein function, the cells are equipped with a tightly regulated network of chaperones that support protein folding and actively participate in protein quality control (PQC) and turnover. Due to the dual origin of the mitochondrial proteome, the cytosolic and mitochondrial PQC networks coordinate to ensure protein import and assembly in the organelle. LÄS MER

  5. 4. Biochemical studies of thiamine deficiency in Baltic salmon (Salmo salar)

    Författare :Gun Åkerman; Lennart Balk; Björn Brunström; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Environmental toxicology; Miljötoxikologi; Applied Environmental Science; tillämpad miljövetenskap;

    Sammanfattning : The first part of this thesis is about the development of a method to inject various substances into the yolk of fish eggs. The method was named nanoinjection and enabled the injection of volumes as small as 10-9 L into the yolk of single fish eggs directly after fertilization, with insignificant mortality due to the injection. LÄS MER