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1. 1. Effects of dopamine and excitotoxicity in experimental models of Huntington's disease

   Författare :Åsa Petersén; Neurobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurology; excitotoxicity; dopamine; Huntington s disease; striatum; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

   Sammanfattning : Huntington's disease (HD) is a hereditary neurodegenerative disorder caused by an expansion of a CAG repeat in the HD gene, that leads to dysfunction and death of striatal neurons. The pathogenetic mechanisms underlying HD are not known, but excitotoxicity and dopamine (DA) have been suggested to play a role. LÄS MER