Sökning: "Åsa Hagner McWhirter"

Hittade 1 avhandling innehållade orden Åsa Hagner McWhirter.

1. 1. Glucuronyl C5-epimerases in the biosynthesis of glycosaminoglycans

   Författare :Åsa Hagner McWhirter; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Biokemi; Biochemistry; Biokemi; Medical and Physiological Chemistry; medicinsk och fysiologisk kemi;

   Sammanfattning : This thesis is focused on two enzymes, both glucuronyl CS-epimerases, that catalyse the conversion of D-glucuronic acid (GlcA) into L-iduronic acid (IdoA) residues in the repeating disaccharide units of heparin/heparan sulphate (HS) and dermatan sulphate (DS) polymers. These glycosaminoglycans are produced as proteoglycans, in which linear polysaccharide chains are attached covalently to a protein core. LÄS MER