Sökning: "[35S]GTPgS binding autoradiography"

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  1. 1. Methological advances in the examination of the dopamine system in brain

    Författare :Judit Sóvágó; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Dopamine-D2 D3 receptors; brain; [35S]GTPgS binding autoradiography; positron emission tomography; partial volume effect;

    Sammanfattning : The dopamine (DA) system in brain has attracted considerable attention in neuroscience due to its involvement in fundamental brain functions and its postulated role in the pathophysiology of several neuropsychiatric disorders. Radioligand binding techniques in vitro and in vivo, such as receptor binding autoradiography and positron emission tomography (PET) have substantially contributed to our understanding of the DA system. LÄS MER