Sökning: "[18F]fallypride"

Hittade 2 avhandlingar innehållade ordet [18F]fallypride.

1. 1. Pre- and postsynaptic dysregulation of dopamine signalling in Parkinson's disease

   Författare :Gurdal Sahin; Brain Repair and Imaging in Neural Systems (BRAINS); []
   Nyckelord :[18F]fallypride; 3-OMD; AAV; blood-brain barrier; dyskinesia; HVA; L-DOPA; microdialysis; modeling; Parkinson’s disease; pharmacokinetics; positron-emission tomography; prediction; RNA interference; shRNA;

   Sammanfattning : .... LÄS MER

3. 2. Dopamine D2 receptor pharmacology : in vitro analyses and in vivo pet imaging

   Författare :Mette Skinbjerg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The goals of the present thesis were to study high affinity agonist binding at the D2 dopamine receptor and to explore the role of agonist induced internalization of the receptor in positron emission tomography (PET) imaging studies. For this purpose, we combined in vitro studies of radioligand binding and receptor internalization with in vivo studies in rodents using PET. LÄS MER