Sökning: "[18F]Vorozole analogs"

Hittade 1 avhandling innehållade orden [18F]Vorozole analogs.

1. 1. Imaging brain aromatase by using PET : A way to study anabolic steroid abuse

   Författare :Kayo Takahashi; Mats Bergström; Bengt Långström; Yasuyoshi Watanabe; Torbjörn Bäckström; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; aromatase; brain; molecular imaging; PET; [11C]Vorozole; amygdala; hypothalamus; anabolic-androgenic steroids; abuse; [18F]Vorozole analogs; Neuroscience; Neurovetenskap;

   Sammanfattning : Aromatase is an enzyme that facilitates the conversion of androgens to estrogens and may play a role in mood and mental status. The main theme of this thesis is the imaging of brain aromatase by use of the PET technique. The PET tracer for aromatase, 11C-labeled vorozole (VOZ) was developed and evaluated by with in vitro and in vivo methods. LÄS MER