Sökning: ": BRAF"

Visar resultat 1 - 5 av 51 avhandlingar innehållade orden : BRAF.

  1. 1. Knowledge demanded for action : studies of knowledge mediation in organisations

    Författare :Ewa Braf; Linköpings universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Computer science; Datavetenskap;

    Sammanfattning : Knowledge enables action and is used in action, but organisations per se do not possess knowledge or perform actions. Organisations act through their members - human actors - who demand actionable knowledge to enable knowledgeable actions. LÄS MER

  3. 2. Organisationers kunskapsverksamheter : en kritisk studie av “knowledge management”

    Författare :Ewa Braf; Göran Goldkuhl; Stefan Cronholm; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Informationsteknik; Informationsteknik; kunskapsmanagement; KM; organisationers kunskapsverksamheter; Information technology; Informationsteknik;

    Sammanfattning : Att utveckla, tillvarata och återanvända kunskap är centrala företeelser för organisationers framåtskridande och utveckling. Härmed har kunskapsmanagement (KM) en viktig roll för och i organisationer. LÄS MER

  4. 3. Molecular understanding of KRAS- and BRAF-mutated colorectal cancers

    Författare :Ida Lundberg; Richard Palmqvist; Maria Wikberg; Sofia Edin; Anita Sjölander; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; BRAF; KRAS; SOX2; CDX2; cancer stem cell; Th1 lymphocytes; miRNA; prognosis;

    Sammanfattning : Colorectal cancer (CRC) is the third most commonly diagnosed malignancy in both men and women, and one of the leading causes of cancer-related deaths worldwide. One frequently mutated pathway involved in oncogenesis in CRC is the RAS/RAF/MAP kinase pathway. LÄS MER

  5. 4. Clinical aspects of molecular profiles in metastatic malignant melanoma

    Författare :Henrik Ekedahl; Lund Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Melanom; Prognos; BRAF; TERT; Genuttryck; Next generation sequencing; Melanoma; Prognosis; BRAF; TERT; Gene Expression; Next generation sequencing;

    Sammanfattning : Malignant melanoma is a heterogeneous, malignant neoplastic disease, most often originating in the skin. Melanoma is characterized by a high mutational load and has a vastly variable prognosis, depending on disease stage. LÄS MER

  7. 5. Metabolic Risk Factors and Molecular Subtypes of Colorectal Cancer

    Författare :Robin Myte; Bethany van Guelpen; Richard Palmqvist; Jenny Häggström; Matty Weijenberg; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; risk factors; metabolic syndrome; one-carbon metabolism; molecular subtypes; KRAS; BRAF; MSI; molecular pathological epidemiology; Cancer Epidemiology; cancerepidemiologi;

    Sammanfattning : Background: Colorectal cancer (CRC) is a heterogeneous disease developing from distinct pathways, resulting in tumor subtypes with large differences in clinical and molecular characteristics. Molecular characteristics are increasingly being used clinically to guide therapy. LÄS MER