Determination of the structures of three bacterial polysaccharides and synthesis and use of new spacers for glycoconjugate formation

Sammanfattning: The first part of this work describes studies on the structures of three bacterial polysaccharides, i.e., the extracellular polysaccharides of Streptococcus pneumoniae type 2 and Butyrivibrio fibrisolvens strain X6C61 and the O-antigenic side-chain of the lipopolysaccharide of Escherichia coli 086.The second part describes the synthesis of new spacer molecules for oligosaccharide immobilization and their use in glycoconjugate formation.