Alzheimer's Disease: The role of alpha1-antichymotrypsin-amyloid peptide (Abeta 1-42) interaction in the pathogenesis of Alzheimer's disease

Detta är en avhandling från Yong-Xin Sun, Wallenberg Lab, plan, University Hospital, UMAS, S-205 02, Malmö

Författare: Yongxin Sun; Lunds Universitet.; Lund University.; [2003]

Nyckelord: MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurofysiologi; neuropsykologi; neurophysiology; Neurologi; neuropsychology; Neurology; lipid metabolism.; inflammation; á1-antichymotrypsin; Alzheimer’s disease; amyloid-â peptide;

Sammanfattning: Alzheimer?s disease (AD) is an age-related, irreversible brain disorder that occurs gradually and results in memory loss, behavioural and personality changes. The disease is characterized by an abnormal accumulation of amyloid-beta (Ab) peptide in the extracellular space and the protein Tau within nerve cells of certain regions of the brain. A

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