Sökning: "vitamin D deficiency"

Visar resultat 1 - 5 av 51 avhandlingar innehållade orden vitamin D deficiency.

  1. 1. Aspects of Vitamin D : Prevalence of deficiency and impact on musculoskeletal parameters

    Författare :Anne Björk; Östen Ljunggren; Gunnar Johansson; Andreas Kindmark; Anna Spångeus; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vitamin D; CYP2R1; Vitamin D receptor Gene; Polymorphisms; Muscle Strength; Endokrinologi och Diabetologi; Endocrinology and Diabetology;

    Sammanfattning : Vitamin D is central in calcium turnover, and adequate levels are important for skeletal health. It is not clear how large contributions from food and sunlight are in Swedish primary care patients, considering the low radiation of UVB in Sweden and fortification of some foods, and whether differences exist between patients of immigrant and Swedish origin. LÄS MER

  2. 2. Regulation of Vitamin D 25-hydroxylases : Effects of Vitamin D Metabolites and Pharmaceutical Compounds on the Bioactivation of Vitamin D

    Författare :Maria Ellfolk; Kjell Wikvall; Maria Norlin; Olavi Pelkonen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CYP2D25; vitamin D 25-hydroxylase; transcriptional regulation; vitamin D; CYP2R1; CYP2J2; CYP27A1; phenobarbital; efavirenz; fibroblast; LNCaP; Pharmaceutical biochemistry; Farmaceutisk biokemi;

    Sammanfattning : A 700bp portion of the promoter of CYP2D25, the porcine microsomal vitamin D 25-hydroxylase was isolated and sequenced. The computer analysis of the sequence revealed the existence of a putative VDRE at 220 bp upstream of the transcription start site. LÄS MER

  3. 3. Vitamin D deficiency in Northern Sweden : a cross-sectional study of an immigrant population at latitude 63° N, including an open partially randomized, controlled trial studying the effect of supplementation with different doses of cholecalciferol

    Författare :Lena Granlund; Eva Fhärm; Christer Andersson; Marie Lindkvist; Anna Ramnemark; Ingrid B Bergström; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vitamin D deficiency; 25-hydroxyvitamin D; cross-sectional study; immigrant; muscle strength; grip strength; anxiety; depression; health related quality of life; clinical trial; cholecalciferol; family medicine; allmänmedicin;

    Sammanfattning : Background: Vitamin D is a prohormone that plays a key role in the calcium and phosphate balance and has physiological functions throughout the entire body. Vitamin D is supplied by exposure to ultraviolet light or by food. The prevalence of vitamin D deficiency in immigrants in Northern Sweden was unknown. LÄS MER

  4. 4. Boning up on Vitamin D : Observational Studies on Bone and Health

    Författare :Greta Snellman; Karl Michaëlsson; Haakon Meyer; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vitamin D; fracture; BMD; assays; genes; mortality; cohort studies; Orthopaedics; Ortopedi;

    Sammanfattning : The primary function of vitamin D in humans is to maintain sufficient circulating calcium concentrations. Low vitamin D levels could result in excessive calcium resorption from bone. Vitamin deficiency may therefore decrease bone mineral density (BMD), resulting in an increased risk of fracture. LÄS MER

  5. 5. Vitamin D, muscle strength, prolonged labour, Caesarean sections and lifestyle : Clinical and intervention studies in pregnant Somali and Swedish women and new mothers

    Författare :Paul Kalliokoski; Monica Löfvander; Maria Bullarbo; Uppsala universitet; []
    Nyckelord :: caesarean section; dystocia; immigrant; muscle strength; obstetric labour complications; osteomalacia; physical performance; Somalia; vitamin D; vitamin D deficiency; Family Medicine; Allmänmedicin;

    Sammanfattning : Long-term severe vitamin D deficiency may cause osteomalacia with muscle weakness, pain, soft bones, cramps and eventually death. In a pilot study, I found many Somali women to be vitamin D deficient and very weak. LÄS MER