Sökning: "vascular cells"

Visar resultat 1 - 5 av 662 avhandlingar innehållade orden vascular cells.

1. 1. Auxiliary Cells for the Vascularization and Function of Endogenous and Transplanted Islets of Langerhans

   Författare :Liza Grapensparr; Per-Ola Carlsson; Leif Jansson; Mia Phillipson; Aileen King; Uppsala universitet; []
   Nyckelord :Islets of Langerhans; beta cells; diabetes; transplantation; vascularization; Schwann cells; endothelial progenitor cells; neural crest stem cells; Medicinsk vetenskap; Medical Science;

   Sammanfattning : Type 1 diabetes develops through the progressive destruction of the insulin-producing beta-cells. Regeneration or replacement of beta-cells is therefore needed to restore normal glucose homeostasis. Presently, normoglycemia can be achieved by the transplantation of whole pancreas or isolated islets of Langerhans. LÄS MER

3. 2. Myofibroblasts and the Vascular Endothelium : Impact of Fibrin Degradation Products and miRNA on Vascular Motility and Function

   Författare :Peder Fredlund Fuchs; Pär Gerwins; Johan Kreuger; Arne Östman; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Angiogenesis; Vascular biology; Chemotaxis; Endothelial cell; Myofibroblast; Wound healing; miRNA; Heparan sulfate; Medical Science; Medicinsk vetenskap;

   Sammanfattning : Angiogenesis is the formation of new blood vessels from pre-existing vasculature and is important during development as well as wound healing and tissue remodeling. Angiogenesis also occurs during pathological conditions such as diabetic retinopathy and cancer. LÄS MER

4. 3. CYP26B1 as regulator of retinoic acid in vascular cells and atherosclerotic lesions

   Författare :Ali Ateia Elmabsout; Allan Sirsjö; Karin Fransén; Helen Håkansson; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CYP26B1; alternative splice; vascular cells; atherosclerosis; alltrans-retinoic acid; gene polymorphism; inflammation; statins; Medicine; Medicin;

   Sammanfattning : Cardiovascular disease (CVD), currently the most common cause of morbidity and mortality worldwide, is caused mainly by atherosclerosis. Atherosclerosis is a chronic multifocal, immunoinflammatory, fibroproliferative disease of medium and large arteries. LÄS MER

5. 4. Functional genomics of vascular endothelial cells

   Författare :Elisabet Wallgard; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Vasculature; endothelial cells; angiogenesis; vascular endothelial growth factor VEGF ; Notch; transcriptome; genomics; microarray; tumor; retina; morpholino knockdown;

   Sammanfattning : Angiogenesis, the formation of new blood vessels from preexisting ones, is a process involved in normal development as well as in several pathological conditions, such as cancer, ischemic heart disease, wound healing and certain retinal complications. Antiangiogenic targeting is therefore a promising new therapeutic principle. LÄS MER

7. 5. Vascular progenitor cells in arterial remodeling

   Författare :Monika K Grudzinska; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Cardiovascular disease is the leading cause of global mortality and physical disability mainly due to the complications such as myocardial infarction or stroke. Physiological healing reaction takes place in the diseased vessel wall aimed to repair the vessel after an injury. LÄS MER