Sökning: "tumour associated antigen"

Visar resultat 1 - 5 av 35 avhandlingar innehållade orden tumour associated antigen.

  1. 1. Stromal collagens in colorectal cancer and in colorectal liver metastases : tumour biological implications and a source for novel tumour markers

    Författare :Hanna Nyström; Malin Sund; Peter Naredi; Per Sandström; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; colorectal liver metastases; tumour marker; stroma; type IV collagen; metastatic growth pattern; kirurgi; Surgery;

    Sammanfattning : Background: Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality. About 50 % of patients with CRC will develop subsequent liver metastases (CLM). The survival for untreated CLM is only a few months and liver resection provides the only chance for a lasting cure. LÄS MER

  3. 2. Natural and induced immunity against the tumour-associated antigen, Ep-CAM

    Författare :Szilvia Mosolits; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Tumour immunology; Ep-CAM; anti-idiotypic antibodies; vaccination;

    Sammanfattning : The tumour-associated antigen (TAA), Ep-CAM is overexpressed on various human carcinomas, including colorectal carcinoma (CRC). TAAs or their immunodominant epitopes that are spontaneously recognised by the immune system might constitute a suitable target for immunotherapy. LÄS MER

  4. 3. Macrophage antigen expression in breast and colorectal cancers : A consequence of macrophage - tumour cell fusion?

    Författare :Ivan Shabo; Joar Svanvik; Bengt Gustavsson; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Carcinogenesis is a sophisticated biological process consisting of a series of progressive changes in somatic cells from premalignant to malignant phenotype. Despite the vast information available about cancer cells, the origin of cancer and cause of metastasis still remain enigmatic. LÄS MER

  5. 4. Gene and Protein Expression in Human Gliomas

    Författare :Oscar Persson; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tumour associated antigen; immunotherapy; glioma; targeted therapy; microarray; proteomics;

    Sammanfattning : The human gliomas are the most common primary brain tumours. They are highly aggressive with a rapid fatal progression for the patient. The invasive growth pattern and inherent resistance to radiation and chemotherapy account for a lack of efficient therapies. LÄS MER

  7. 5. Transcriptional analysis of mantle cell lymphoma - a global search for cellular origin and therapeutic targets

    Författare :Sara Ek; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; oncology; cancerology; Cytologi; onkologi; Cytology; somatic mutation; microarray; tumour; mantle cell lymphoma; B cell;

    Sammanfattning : This thesis is based upon four original papers describing the characterisation of mantle cell lymphoma (MCL) tumours and cell lines in comparison with different populations of normal B cells. Gene expression profiling, which were used in the studies, has during recent years developed as an important tool in characterisation of different types of malignancies. LÄS MER