Sökning: "trisomy"
Visar resultat 1 - 5 av 25 avhandlingar innehållade ordet trisomy.
1. Trisomies in Hematologic Malignancies
Sammanfattning : Acquired clonal chromosome aberrations, closely associated with leukemogenesis, are found in many hematologic malignancies. Although the balanced rearrangements, such as translocations and inversions, are the ones most commonly thought of in the context of leukemias, gains of chromosomes ? e.g.. LÄS MER
2. Cytogenetic studies of normal kidney tissue and renal cell carcinoma
Sammanfattning : In the present thesis normal kidney tissue and renal cell carcinoma (RCC) were studied by cytogenetic and fluorescence in situ hybridization (FISH) methods to investigate chromosomal aberrations. In the first study, 4 samples of nonneoplastic kidney tissue were cultured for cytogenetic analysis and trisomy 7 was found in all cases in 3-15% of the cells. LÄS MER
3. Characterization of somatic mutations in nonneoplastic cells
Sammanfattning : Acquired genetic alterations, of which many are visible on the chromosome level, are believed to be necessary for tumorigenesis, and most tumors display characteristic patterns of recurrent structural and numerical aberrations. However, two of the most frequently occurring chromosome mutations in malignant and benign solid tumors, i.e. LÄS MER
4. Cytogenetic studies of primary and metastatic breast cancer
Sammanfattning : A series of primary and metastatic breast carcinomas obtained from female and male patients were cytogenetically analysed. Trisomy 12 was identified as a recurrent and sometimes early event in breast carcinogenesis. LÄS MER
5. Surgical treatment of atrioventricular septal defect
Sammanfattning : .... LÄS MER