Sökning: "systemic chemotherapy"
Visar resultat 1 - 5 av 43 avhandlingar innehållade orden systemic chemotherapy.
1. Clinical and Experimental Studies in Peritoneal Metastases from Gastric Cancer
Sammanfattning : Gastric cancer (GC) is one of leading causes of death in the world, and peritoneal metastases (PM) are a major site of recurrence. PM from GC implies a poor prognosis, with median overall survival (mOS) approximately 3 months and no survival at five years. LÄS MER
2. Genotoxic effects of systemic chemotherapy in cancer patients, with special focus on the relation between MSI, LOH and development of secondary cancers
Sammanfattning : Systemic chemotherapy results in both phenotypic and genotypic side effects. Genotoxicity posed by chemotherapy is a major concern since it induces DNA damage and instability in the patients’ genome. LÄS MER
3. Combined chemotherapy and immunotherapy against experimental malignant brain tumors
Sammanfattning : Glioblastoma multiforme (GBM) is the most common and aggressive primary malignant brain tumor in adults. Despite standard treatment including surgery, radiotherapy and temozolomide (TMZ)-based chemotherapy, the prognosis for GBM patients is dismal, and there is a need for novel treatments. LÄS MER
4. Cyclin A and cyclin E as prognostic factors in early breast cancer
Sammanfattning : Breast cancer is one of the most common malignancies in women. Due to early detection and the use of screening programs approximately 60% of all new cases lack lymph node involvement. Today, a substantial proportion of these women will be offered adjuvant systemic chemotherapy. LÄS MER
5. Preclinical Studies for Cryoprevention of Oral Mucositis
Sammanfattning : Oral mucositis (OM) is a debilitating adverse effect, with a prevalence of up to 80% in patients with cancer who are conditioned with high-dose chemotherapy prior to hematopoietic stem cell transplantation. In its mildest form, OM is characterized by erythema. However, as it worsens, it can give rise to painful ulcerations in the oral mucosa. LÄS MER