Sökning: "synaptic vesicle"

Visar resultat 1 - 5 av 40 avhandlingar innehållade orden synaptic vesicle.

  1. 1. Cytoskeletal mechanisms in synaptic vesicle recycling

    Författare :Jenny Gustafsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Synapse; actin cytoskeleton; synaptic vesicle; endocytosis;

    Sammanfattning : This thesis explores cytoskeletal mechanisms involved in the recycling of synaptic vesicles. As an initial step it characterizes synapses formed by giant reticulospinal axons in lamprey and defines their use as a model system. The most common type of reticulospinal synapse, "simple synapse", appeared to be most suitable as an experimental model. LÄS MER

  3. 2. Molecular mechanisms in synaptic vesicle recycling

    Författare :Joel Jakobsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Neurons communicate through specialized contacts called synapses, which consist of pre- and postsynaptic compartments separated by a narrow synaptic cleft. The stimulus- dependent rapid influx of calcium ions into the presynaptic compartment induces fusion of neurotransmitter-filled vesicles with the plasma membrane and release of their content into the synaptic cleft. LÄS MER

  4. 3. Synaptic vesicle endocytosis studied in a living synapse

    Författare :Helge Gad; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :synapse; synaptic vesicles; endocytosis; clathrin; calcium; dynamin; endophilin; amphiphysin; synaptojanin; microinjection; electron microscopy;

    Sammanfattning : Neurons in the central nervous system communicate by transmitting electrical signals at special sites of contact called synapses. Synapses contain neurotransmitter-filled synaptic vesicles, which fuse with the presynaptic plasma membrane. The neurotransmitter diffuses to the neighboring neuron and triggers a new electrical signal. LÄS MER

  5. 4. Vesicle proteins as markers for neuroendocrine tumors

    Författare :Anne-Marie Levin Jakobsen; Göteborgs universitet; []
    Nyckelord :Neuroendocrine tumours; gastrointestinal tract; pancreas; adrenal; vesicle proteins; ; SV2; NESP55; VMAT1; VMAT2; MIBG;

    Sammanfattning : The neuroendocrine (NE) tumours comprise a diversity of tumours which share commonproperties, e.g. the capacity to produce, store and release hormones. A prominent feature ofthe NE phenotype is the production of secretory granules with associated vescicle proteins,e. LÄS MER

  7. 5. Studies of membrane-binding proteins involved in synaptic vesicle recycling

    Författare :Fredrik Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Signaling between neurons occurs at synapses. A presynaptic nerve terminal releases neurotransmitter, which diffuses over the synaptic cleft, and binds to postsynaptic receptors. Release occurs by fusion of neurotransmitter-containing vesicles with the plasma membrane. LÄS MER