Sökning: "synaptic proteins"

Visar resultat 1 - 5 av 110 avhandlingar innehållade orden synaptic proteins.

  1. 1. Advanced Fluorescence Microscopy to Study Plasma Membrane Protein Dynamics

    Författare :Joachim Piguet; Horst Vogel; Ruud Hovius; Jerker Widengren; Antoine Triller; Switzerland Ecole Polytechnique Fédérale de Lausanne (EPFL); []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; fluorescence; microscopy; plasma membrane; membrane proteins; membrane proteins diffusion; single-molecule imaging; single-molecule tracking; pentameric ligand-gated ion channels; nicotinic acetylcholine receptor; serotonin receptor; synapse; neuromuscular junction; post-synaptic scaffold; rapsyn; myopathies; fluorescent proteins; Förster resonance energy transfer; FRET imaging; protein-protein interactions; protein trafficking; photo-activatable proteins; Biological Physics; Biologisk fysik;

    Sammanfattning : Membrane protein dynamics is of great importance for living organisms. The precise localization of proteins composing a synapse on the membrane facing a nerve terminus is essential for proper functioning of the nervous system. In muscle fibers, the nicotinic acetylcholine is densely packed under the motor nerve termini. LÄS MER

  3. 2. Immune responses and synaptic protein expression in epilepsy

    Författare :Una Avdic; Epilepsicentrum; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; epilepsy; non-convulsive status epileptics; synaptic proteins; immune response; microglia; inflammation;

    Sammanfattning : .... LÄS MER

  4. 3. Development of proteomic methods for studying cerebrospinal fluid proteins involved in Alzheimer´s disease

    Författare :Maja Puchades; Göteborgs universitet; []
    Nyckelord :Alzheimer s disease; cerebrospinal fluid; proteomics; mass spectrometry; biomarkers; synaptic proteins; liquid phase IEF; biomarkers;

    Sammanfattning : Alzheimer's disease (AD) is the most common cause of dementia in western countries. The main neuropathological findings in the AD brain are senile plaques, neurofibrillary tangles and degeneration of neurons and synapses. LÄS MER

  5. 4. Vesicle proteins as markers for neuroendocrine tumors

    Författare :Anne-Marie Levin Jakobsen; Göteborgs universitet; []
    Nyckelord :Neuroendocrine tumours; gastrointestinal tract; pancreas; adrenal; vesicle proteins; ; SV2; NESP55; VMAT1; VMAT2; MIBG;

    Sammanfattning : The neuroendocrine (NE) tumours comprise a diversity of tumours which share commonproperties, e.g. the capacity to produce, store and release hormones. A prominent feature ofthe NE phenotype is the production of secretory granules with associated vescicle proteins,e. LÄS MER

  7. 5. Studies of membrane-binding proteins involved in synaptic vesicle recycling

    Författare :Fredrik Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Signaling between neurons occurs at synapses. A presynaptic nerve terminal releases neurotransmitter, which diffuses over the synaptic cleft, and binds to postsynaptic receptors. Release occurs by fusion of neurotransmitter-containing vesicles with the plasma membrane. LÄS MER