Sökning: "sympatric ethnic groups"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden sympatric ethnic groups.

  1. 1. Plasmodium falciparum-mediated modulation of innate immune cells: responses and regulation

    Författare :Ioana Bujila; Ann-Kristin Östlund Farrants; Marita Troye-Blomberg; Artur Scherf; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Plasmodium falciparum; hemozoin; innate immune cells; sympatric ethnic groups; immunologi; Immunology;

    Sammanfattning : Plasmodium falciparum (P. falciparum) infection modulates the response of innate immune cells. The aim of this work was to study the impact of P. falciparum infection and P. LÄS MER

  3. 2. Novel immunization strategies and interethnic differences in response to malaria infection

    Författare :Charles Arama; Marita Troye-Blomberg; Kai Matuschewski; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Malaria; Immunization; Ethnic groups; vaccines; immunologi; Immunology;

    Sammanfattning : A better understanding of the role of antigen-presenting cells (APCs) in host resistance to malaria is essential to unravel the complex interactions between the host and the parasite. This would improve the design of malaria vaccines. LÄS MER

  4. 3. Human candidate polymorphisms and malaria susceptibility in sympatric ethnic groups, The Fulani and The Dogon of Mali

    Författare :Bakary Maiga; Ann-Kristin Östlund Farrants; Lars Hviid; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Malaria; Fulani; Dogon; Blood group; SNPs; IL-4; FcγRIIa; antibody level; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : In malaria endemic regions, resistance to malaria constitutes a critical selective pressureon genetic polymorphisms that regulate immune defense and inflammatory pathways.Differences in malaria susceptibility between sympatric ethnic groups have been described inMali. LÄS MER

  5. 4. Single nucleotide polymorphisms related to immune responses in Plasmodium falciparum malaria

    Författare :Amre Nasr; Klavs Berzins; Marita Troye-Blomberg; Gehad ElGhazali; Thor Theander; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; FcγRIIa-R H131; CRP genotypes; GM KM allotypes; IgG; and malaria; Sudan; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : The current research is directed towards dissection of host genetic factors involved in host immune response and the malaria disease outcome. A possible association between FcγRIIa polymorphism and anti-malarial antibody (A.M.A) responses were investigated in Sudanese patients in relation to clinical outcome of falciparum malaria. LÄS MER

  7. 5. Host genetic factors and antibody responses with potential involvement in the susceptibility to malaria

    Författare :Elisabeth Israelsson; Klavs Berzins; Jean Langhorne; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : The relatively lower susceptibility to malaria seen in the Fulani ethnic group in Africa, as compared to other sympatric ethnic groups, has been related to genetic regulation of the immune responses. This thesis aimed to describe important pathways related to the regulation of antibodies in the immune responses during a malaria infection. LÄS MER