Sökning: "substrate selectivity"

Visar resultat 1 - 5 av 103 avhandlingar innehållade orden substrate selectivity.

  1. 1. Characterization and Directed Evolution of an Alcohol Dehydrogenase : A Study Towards Understanding of Three Central Aspects of Substrate Selectivity

    Författare :Emil Hamnevik; Mikael Widersten; Gerrit Poelarends; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Alcohol dehydrogenase; ADH-A; Biocatalysis; Directed evolution; Enantioselectivity; Enzyme kinetics; Enzyme mechanisms; Protein Engineering; Regioselectivity; Substrate selectivity; Biokemi; Biochemistry;

    Sammanfattning : Many different chemicals are used in the everyday life, like detergents and pharmaceuticals. However, their production has a big impact on health and environment as much of the raw materials are not renewable and the standard ways of production in many cases includes toxic and environmentally hazardous components. LÄS MER

  3. 2. Serine Hydrolase Selectivity : Kinetics and applications in organic and analytical chemistry

    Författare :Anders Hamberg; Karl Hult; Dick Janssen; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Candida antarctica lipase B; monoacylation of diols; kinetic resolution; thermodynamics in enzyme catalysis; enzyme engineering; Biochemistry; Biokemi;

    Sammanfattning : The substrate selectivities for different serine hydrolases were utilized in various applications, presented in papers I-VI. The articles are discussed in the thesis in view of the kinetics of the enzyme catalysis involved. LÄS MER

  4. 3. Investigation of Kinetically Labile Supramolecu-lar System Addressing Substrate Selectivity in the Catalytic Epoxidations of Olefins

    Författare :Fabrice Odille; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Naturvetenskap; Natural science; enantioselectivity; Salen Mn III ; substrate selectivity; porphyrin; Jacobsen-Katsuki epoxidation; supramolecular catalysis; Hydrogen-bond; 2-pyridone;

    Sammanfattning : This thesis is devoted to the development and investigation of a supramolecular system used to catalyze Jacobsen-Katsuki epoxidations with the aim to attain substrate selectivity without product inhibition. The supramolecular catalyst is composed of two well-defined entities or units: a catalytic and a receptor. LÄS MER

  5. 4. Building blocks for polymer synthesis by enzymatic catalysis

    Författare :Stefan Semlitsch; Mats Martinelle; Sergio Riva; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Enzyme; Enzyme Engineering; Biocatalysis; Lipase; CalB; MsAcT; Substrate specificity; Selectivity; Polymer Chemistry; Polymer Synthesis; Bioteknologi; Biotechnology;

    Sammanfattning : The search for alternatives to oil-based monomers has sparked interest for scientists to focus on the use of renewable resources for energy production, for the synthesis of polymeric materials and in other areas. With the use of renewable resources, scientists face new challenges to first isolate interesting molecules and then to process them. LÄS MER

  7. 5. Enzyme catalysis towards bio-based UV-curable buildingblocks

    Författare :Maja Finnveden; Mats Martinelle; Katja Loos; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Enzyme; Enzymatic Polymerizations; Biocatalysis; Lipase; CalB; MsAcT; Substrate specificity; Selectivity; Polymer Chemistry; UV-curring; Bioteknologi; Biotechnology;

    Sammanfattning : Polymeric materials are found in virtually all areas of daily life; they are found in everything from packages keeping our food safe to the buildings where we spend our days, and the production is a worldwide industry. Although polymeric materials play a big part in sustainable solution’s, a lot can be done to develop more environmental methods for producing them. LÄS MER