Sökning: "steric stabilisation"

Hittade 4 avhandlingar innehållade orden steric stabilisation.

  1. 1. Sterically stabilised liposomes and related lipid aggregates Fundamental studies on aggragate structure and stability

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Markus Johnsson; Uppsala universitet.; [2001]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Physics; liposome; steric stabilisation; colloidal stability; cryo-TEM; drug delivery; Fysik; NATURAL SCIENCES Physics; NATURVETENSKAP Fysik; Physical Chemistry; fysikalisk kemi;

    Sammanfattning : Various aspects of and approaches towards the steric stabilisation of liposomes have been investigated, mainly by use of fluorescence techniques and cryo-transmission electron microscopy (cryo-TEM). It is shown that PEG(2000)-lipids can be incorporated in the liposome membrane up to a critical concentration of 8-10 mol% without any observable structural perturbations. LÄS MER

  2. 2. Liposomes for Drug Delivery from Physico-chemical Studies to Applications

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Nill Bergstrand; Uppsala universitet.; [2003]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Physical chemistry; liposome; steric stabilisation; BNCT; cryo-TEM; EGF; targeting; stability; permeability; pH-sensitive liposomes; triggered release; Fysikalisk kemi; NATURAL SCIENCES Chemistry Physical chemistry; NATURVETENSKAP Kemi Fysikalisk kemi; Physical Chemistry; fysikalisk kemi;

    Sammanfattning : Physico-chemical characterisation of structure and stability of liposomes intended for drug delivery is the central issue in this thesis. In addition, targeted liposomes to be used in boron neutron capture therapy (BNCT) were developed.Lysolipids and fatty acids are products formed upon hydrolysis of PC-lipids. LÄS MER

  3. 3. Intermediate State Stabilisation in Enzyme Catalysis Structural studies of two serine proteases and a photosynthetic reaction centre

    Detta är en avhandling från Chalmers University of Technology

    Författare :Gergely Katona; Chalmers tekniska högskola.; Chalmers University of Technology.; [2004]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Bioteknik; Bioengineering; enzyme catalysis; serine protease; photosynthetic reaction centre; X-ray crystallography; enzyme kinetics; structural mechanism; enzyme intermediate;

    Sammanfattning : Enzymes play a key role in every organism’s life. They catalyse chemical reactions and may also respond to external stimulus. The reoccurring theme of this thesis is how biologically relevant information can be gleaned from X-ray structures of the enzymes. LÄS MER

  4. 4. Structure and stability of liposomes : Interactions with micelle- forming surfactants

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Mats Silvander; Uppsala universitet.; [1999]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Physics; Fysik; NATURAL SCIENCES Physics; NATURVETENSKAP Fysik; Physical Chemistry; fysikalisk kemi;

    Sammanfattning : The stability of phospholipid lipomes interacting with micelle-forming surfactants was studied under physiological conditions (150 mM NaCl and pH=7.4 unless otherwise stated) mainly by use of cryo-TEM and fluorescence. LÄS MER