Sökning: "spatially resolved transcriptomics"

Hittade 2 avhandlingar innehållade orden spatially resolved transcriptomics.

  1. 1. In situ Sequencing Methods for spatially-resolved transcriptome analysis

    Detta är en avhandling från Stockholm : Department of Biochemistry and Biophysics, Stockholm University

    Författare :Marco Mignardi; Stockholms universitet.; [2014]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Padlock probes; rolling circle amplification; in situ sequencing; spatially-resolved transcriptomics; molecular diagnostics; biokemi; Biochemistry;

    Sammanfattning : It is well known that cells in tissues display a large heterogeneity in gene expression due to differences in cell lineage origin and variation in the local environment at different sites in the tissue, a heterogeneity that is difficult to study by analyzing bulk RNA extracts from tissue. Recently, genome-wide transcriptome analysis technologies have enabled the analysis of this variation with single-cell resolution. LÄS MER

  2. 2. Transcriptome-wide analysis in cells and tissues

    Detta är en avhandling från Stockholm : KTH Royal Institute of Technology

    Författare :Sanja Vickovic; KTH.; [2017]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; RNA-sequencing; single cells; spatially resolved transcriptomics; 3D profiling.; Biotechnology; Bioteknologi;

    Sammanfattning : High-throughput sequencing has greatly influenced the amount of data produced and biological questions asked and answered. Sequencing approaches have also enabled rapid development of related technological fields such as single-cell and spatially resolved expression profiling. LÄS MER