Sökning: "solution hybridization"
Visar resultat 1 - 5 av 34 avhandlingar innehållade orden solution hybridization.
1. Concatemerization of Synthetic Oligonucleotides
Sammanfattning : DNA nanotechnology has become an important research field because of its advantages in high predictability and accuracy of base-paring recognition. For example, the DNA concatemer, one of the simplest DNA constructs in shape, has been used to enhance signals in biosensing. LÄS MER
2. On Hybrid Fuel Cell and Battery Systems for Maritime Applications
Sammanfattning : Hydrogen is seen as a key player in leading to a sustainable energy sector and decarbonizing the transport sector. Proton Exchange Membrane Fuel Cells (PEMFCs) consume hydrogen and oxygen to generate water, heat and electricity. LÄS MER
3. The Light-up Probe
Sammanfattning : The work presented in this thesis concerns the development of light-up probes and their potential applications in PCR based molecular diagnostics. The light-up probe is a nucleic acid analog (here PNA) oligomer linked to an asymmetric cyanine dye (here thiazole orange) and it combines the excellent hybridization properties of PNA with the large fluorescence enhancement of the dye upon binding to DNA. LÄS MER
4. Genotyping RNA and DNA using padlock probes
Sammanfattning : Novel techniques are needed to investigate the genetic variation revealed in the first draft of the human genome sequence. Padlock probes are recently developed reagents, suitable for detecting single-nucleotide variations of DNA and RNA in situ or in solution. LÄS MER
5. Molecular pharmacology of amiodarone
Sammanfattning : Amiodarone (Am) is a potent class III antiarrhythmic drug. Its use is limited due to serious side effects and it was therefore used only when other therapeutic interventions proved to be ineffective. LÄS MER