Sökning: "solubility"

Visar resultat 1 - 5 av 476 avhandlingar innehållade ordet solubility.

  1. 1. Solubility and polymorphism of molecular compounds

    Författare :Sandra Gracin; Åke C. Rasmuson; David J. W. Grant; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Chemical engineering; solubility; prediction of solubility; UNIFAC; activity coefficients; activity of the solid phase; polymorphism; controlled crystallization; sonication.; Kemiteknik; Chemical engineering; Kemiteknik;

    Sammanfattning : This thesis deals with the controlled crystallization of small organic molecules and is focused on solubility and polymorphism. The solubility was determined for phenylacetic acid, p-hydroxyphenylacetic acid, p-aminophenylacetic acid, p-hydroxybenzoic acid and ibuprofen in both water and in a range of organic solvents. LÄS MER

  3. 2. The Chemistry of Plutonium Solubility

    Författare :Hans Nilsson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; sorption; colloids; solubility; modeling; oxidation states; plutonium; hydrolysis; actinides;

    Sammanfattning : When designing a repository for spent nuclear fuel it is necessary to assess the possibility that radionuclides will be transported from the repository by groundwater. A limiting factor for such transport is the solubility of any given radionuclide. LÄS MER

  4. 3. Computational Analysis of Aqueous Drug Solubility – Influence of the Solid State

    Författare :Carola Wassvik; Per Artursson; Anders G Holmén; Valentino J. Stella; Uppsala universitet; []
    Nyckelord :Pharmaceutics; intrinsic solubility; solubility prediction; drug solubility; solid state; melting point; enthalpy of melting; entropy of melting; solvation; free energy of hydration; QSPR; multivariate analysis; PCA; PLS; Galenisk farmaci;

    Sammanfattning : Aqueous solubility is a key parameter influencing the bioavailability of drugs and drug candidates. In this thesis computational models for the prediction of aqueous drug solubility were explored. LÄS MER

  5. 4. Pharmaceutical cocrystals : formation mechanisms, solubility behaviour and solid-state properties

    Författare :Amjad Alhalaweh; Peter York; Luleå tekniska universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; crystal engineering; cocrystal; formation; solubility; pH; dissolution; surface properties; solid-state properties; Health Science; Hälsovetenskap;

    Sammanfattning : The primary aim of pharmaceutical materials engineering is the successful formulation and process development of pharmaceutical products. The diversity of solid forms available offers attractive opportunities for tailoring material properties. LÄS MER

  7. 5. Solid-liquid Phase Equilibria and Crystallization of Disubstituted Benzene Derivatives

    Författare :Fredrik Nordström; Åke Rasmuson; Gerard Coquerel; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Salicylic acid; m-hydroxybenzoic acid; p-hydroxybenzoic acid; salicylamide; m-aminobenzoic acid; p-aminobenzoic acid; solubility; solid-liquid equilibria; thermodynamics; activity of the solid phase; ideal solubility; activity coefficient; van t Hoff enthalpy of solution; solid state; solution properties; metastable zone width; primary nucleation; nucleation kinetics; Chemical engineering; Kemiteknik;

    Sammanfattning : The Ph.D. project compiled in this thesis has focused on the role of the solvent in solid-liquid phase equilibria and in nucleation kinetics. Six organic substances have been selected as model compounds, viz. LÄS MER