Sökning: "sodium channel"
Visar resultat 1 - 5 av 46 avhandlingar innehållade orden sodium channel.
1. Calcium transport in the Pacific oyster, Crassostrea gigas - in a changing environment
Sammanfattning : Pacific oyster, Crassostrea gigas, is globally one of the most important farmed bivalve species. A prominent features of the C. gigas is the thick CaCO3 shell covering the body of the animal and protecting it from the environment. LÄS MER
2. Structure, Mechanism, and Regulation of Sodium/Proton Exchangers
Sammanfattning : Sodium/proton exchangers (NHEs) are secondary active transporters that are ubiquitously found in all kingdoms of life. They facilitate the exchange of protons for sodium ions or other inorganic ions across biological membranes, regulating pH, sodium levels, and osmotic pressure. LÄS MER
3. Tetrodotoxin-resistant sodium channels in neuropathic pain
Sammanfattning : Injury to the peripheral nervous system can cause neuropathic pain. Abnormal sodium channel activity has been implicated as a source of ectopic firing and changes in nociceptive threshold following nerve injury. LÄS MER
4. Gating and modulation mechanism of voltage gated sodium channels
Sammanfattning : Voltage-gated sodium channels (Nav channels) play an essential role in nerve impulse conduction in excitable cells. Thus, these channels are involved in several neurological and muscular disorders. Understanding their mechanism of functioning is essential for designing drugs targeting them. LÄS MER
5. Clinical and genetical studies in cystic fibrosis and pseudohypoaldosteronism
Sammanfattning : Cystic fibrosis (CF) is the most common severe autosomal recessive disorder among Caucasians and is caused by mutations of the chloride channel, CFTR (cystic fibrosis transmembrane conductance regulator) gene. Despite a markedly improved median survival many CF patients still die at a young age. LÄS MER