Sökning: "single cells"
Visar resultat 11 - 15 av 1555 avhandlingar innehållade orden single cells.
11. Optical manipulation and spectroscopy of single functional globin-containing cells in microfluidic systems
Sammanfattning : Recent advances in microbiology and biomedicine require development of tools to monitor the response of single cells to environmental stimuli under controlled physiological conditions. In this thesis, I describe how this can be achieved by combining various spectroscopic techniques with optical tweezers and microfluidic systems. LÄS MER
12. Genotyping and Mutation Detection In Situ : Development and application of single-molecule techniques
Sammanfattning : The human body is composed of trillions of cells closely working together to maintain a functional organism. Every cell is unique in molecular composition and can acquire genetic variations that might cause it to turn pathological. LÄS MER
13. Transcriptome-wide analysis in cells and tissues
Sammanfattning : High-throughput sequencing has greatly influenced the amount of data produced and biological questions asked and answered. Sequencing approaches have also enabled rapid development of related technological fields such as single-cell and spatially resolved expression profiling. LÄS MER
14. Regulation of Type I Interferon Production in Plasmacytoid Dendritic Cells : Effect of Genetic Factors and Interactions with NK Cells and B Cells
Sammanfattning : The type I interferon (IFN) system plays a central role in the etiopathogenesis of many autoimmune diseases, e.g. systemic lupus erythematosus (SLE). Activation of the type I IFN system in SLE is promoted by endogenous nucleic acid-containing immune complexes (ICs) which stimulate plasmacytoid dendritic cells (pDCs). LÄS MER
15. Pinpointing biomarkers of importance for children with combined type 1 diabetes and celiac disease
Sammanfattning : Type 1 diabetes (T1D) and celiac disease are both characterized by an autoimmune feature. The diseases also share the same risk genes, and thereby patients have an increased risk of developing the other disease subsequently. LÄS MER