Sökning: "sib-pair"

Visar resultat 1 - 5 av 9 avhandlingar innehållade ordet sib-pair.

  1. 1. On Power Estimation and Score Predictions in Affected Sib-Pair Linkage Analysis

    Författare :Mikael Knutsson; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; affected sib-pair; linkage analysis; nonparametric linkage score; sib prevalence; statistical genetics; nonparametric linkage score;

    Sammanfattning : This thesis consists of three papers in statistical genetics, with the emphasis on affected sib-pair linkage analysis. In Paper A, a method to derive the power of linkage analysis in genome scans, using a stepwise approach, is presented. LÄS MER

  3. 2. Two-Locus affected sib-pair identity by descent probabilities

    Författare :Olof Bengtsson; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER

  4. 3. Clinical and genetical aspects of Celiac Disease

    Författare :Audur Gudjonsdottir; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; celiac disease; sib-pair; screening; genome-wide scan; linkage analysis; heritability; genotypes; DQ2-negative; phenotypes; autoimmune disease;

    Sammanfattning : Celiac disease (CD), or gluten-sensitive enteropathy, is one of the most common chronic diseases in childhood but is diagnosed in all ages. CD is a genetically driven immunological intolerance to dietary gluten. Th e treatment is a gluten-free diet. LÄS MER

  5. 4. Identifying Risk Genes for Cervical Cancer : Using Affected Sib-Pairs and Case-Control Materials from Sweden

    Författare :Malin Engelmark; Ulf Gyllensten; Dan Holmberg; Uppsala universitet; []
    Nyckelord :Medicine; Cervical cancer; HPV; Affected sib-pairs; HLA; Fas; Genomewide scan; 9q32; TSCOT; Medicin;

    Sammanfattning : Cervical cancer is a multifactorial disease. Infection by oncogenic types of the human papillomavirus (HPV) is the major environmental risk factor and host genetic susceptibility also influences disease development. The aim of this thesis is to identify and analyse risk genes involved in the genetic predisposition to cervical carcinoma. LÄS MER

  7. 5. Assessment of Body Composition Using Magnetic Resonance Imaging

    Författare :Joel Kullberg; Hans Frimmel; Tomas Gustavsson; Uppsala universitet; []
    Nyckelord :Bildanalys; Magnetic Resonance Imaging; Digital Image Processing; Segmentation; Morphology; Body Composition; Whole Body Imaging; Subcutaneous Adipose Tissue; Visceral Adipose Tissue; Anthropometry; Bildanalys;

    Sammanfattning : Methods for assessment of body composition allow studies of the complex relationships between body composition and the wellbeing of humans. The amount and distribution of adipose tissue is of great importance in these studies. LÄS MER