Sökning: "serotonin antagonists"
Visar resultat 1 - 5 av 34 avhandlingar innehållade orden serotonin antagonists.
1. Serotonin in Fear and Anxiety
Sammanfattning : That the neurotransmitter serotonin (5-HT) has a central role in fear and anxiety is supported by numerous experimental and clinical studies. Arguably the most illustrative example is the effect of serotonergic-acting drugs, and in particular the selective serotonin reuptake inhibitors (SSRIs), in the treatment of anxiety disorders. LÄS MER
2. 5-HT2A : a serotonin receptor with a possible role in joint diseases
Sammanfattning : BackgroundSerotonin (5-HT), an amino acid derivative and neurotransmitter, has for long been studied in relation to inflammation. It is an endogenous ligand for several different types of serotonin receptors. The serotonin receptor 5-HT2A has been reported to have a role in the pathophysiology of arthritis in animal experiment models. LÄS MER
3. Serotonergic and steroidal influences on impulsive behaviour in rats
Sammanfattning : Impulsiveness is a trait contributing to the personality of all human beings to a greater and lesser extent. In a pathological form it can lead to impulsive behaviour which is an important component of many psychiatric and neurological disorders. LÄS MER
4. Spinal Acetylcholine Release : Mechanisms and Receptor Involvement
Sammanfattning : Impulses coming from peripheries are modified in the spinal cord and transmitted to the brain. Several neurotransmitters have been involved in the processing of impulses in the spinal dorsal horn. Acetylcholine (ACh) is one of many neurotransmitters involved in the regulation of nociception in the spinal cord. LÄS MER
5. Tissue remodelling in pulmonary fibrosis linked to 5-HT2 receptor activation
Sammanfattning : After an injury, an immediate reparative response is triggered to replace the damaged tissue, however, in fibrosis, cells remain active despite wound resolution causing a steady build-up of fibrotic tissue. In pulmonary fibrosis,there is a constant regeneration and remodelling of lung tissue where the thin architecture of alveoli become thickened, hampering efficient diffusion of oxygen, as seen in diseases like idiopathic pulmonary fibrosis (IPF). LÄS MER