Sökning: "selective infection"

Visar resultat 1 - 5 av 101 avhandlingar innehållade orden selective infection.

  1. 1. The biology of filamentous phage infection - implications for display technology

    Författare :Fredrik Karlsson; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biotechnology; Bioteknik; infection mechanism; selective infection; TolA; Escherichia coli; pIII; Filamentous phage; Phage display technology;

    Sammanfattning : Phage display technology is a biotechnological tool that can be used to obtain molecules/reagents able to discriminate between target molecules. Reagents with such features can be used in diverse settings like biological chemistry, diagnostics and in therapeutic applications. LÄS MER

  3. 2. Selective protein functionalisation via enzymatic phosphocholination

    Författare :Philipp Ochtrop; Christian Hedberg; Tom Grossmann; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; chemical biology; organic synthesis; site-selective protein labeling; PTM; phosphocholination; nucleotides; bioorthogonal chemistry; proteomics; IMPDH2;

    Sammanfattning : Proteins are the most abundant biomolecules within a cell and are involved in all biochemical cellular processes ultimately determining cellular function. Therefore, to develop a complete understanding of cellular processes, obtaining knowledge about protein function and interaction at a molecular level is critical. LÄS MER

  4. 3. Improved diagnosis and prediction of community-acquired pneumonia

    Författare :Alicia Edin; Anders F. Johansson; Anders Sjöstedt; Annika Allard; Thomas Schön; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Community-acquired pneumonia; infection; diagnosis; qPCR; metabolites; metabolomics;

    Sammanfattning : Community-acquired pneumonia (CAP) is a major cause of morbidity and mortality worldwide. Although there is wide variation in the microbial etiology, CAP may manifest with similar symptoms, making institution of proper treatment challenging. LÄS MER

  5. 4. Evolutionary trajectories of Klebsiella pneumoniae : From experimental biofilm evolution to a hospital outbreak

    Författare :Greta Zaborskytė; Linus Sandegren; Vaughn S. Cooper; Uppsala universitet; []
    Nyckelord :Klebsiella pneumoniae; evolution; experimental evolution; biofilms; infection; bacterial pathogens; Mikrobiologi; Microbiology;

    Sammanfattning : Bacterial evolution is closely intertwined with our lives. As their hosts, we shape how bacteria evolve by imposing numerous selective pressures during the time bacteria spend in our bodies. As a result, they adapt in various ways to colonize us or infect us better. LÄS MER

  7. 5. Improving the prevention of sexually transmitted infections (STIs) : a study using Chlamydia trachomatis as a model infection

    Författare :Daniel Novak; Roger Karlsson; Berit Andersen; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Public health; STI; Prevention; Chlamydia; Postal screening; cost effective; condom; Internet; self-selective screening; Folkhälsomedicin; Public health medicine research areas; Folkhälsomedicinska forskningsområden; Family Medicine; allmänmedicin;

    Sammanfattning : Despite the current preventive strategies sexually transmitted infections (STIs) are rising. This thesis presents a model with the aim of improving the prevention of STIs. Chlamydia being the most common STI in Sweden serves as a model infection. The presented model is based on five performed studies. LÄS MER