Sökning: "sekretion"

Visar resultat 11 - 15 av 96 avhandlingar innehållade ordet sekretion.

  1. 11. Hypertension in a defined population. The Skaraborg Hypertension and Diabetes Project

    Författare :Erik Bøg-Hansen; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Socialmedicin; samhällsmedicin; Kardiovaskulära systemet; Social medicine; Cardiovascular system; sekretion; diabetologi; diabetology; Endokrinologi; secreting systems; Endocrinology; primary care.; treatment; survival; cardiovascular disease risk factors; insulin resistance; Hypertension; type 2 diabetes;

    Sammanfattning : To examine cardiovascular disease risk factors, control of hypertension and survival in patients with hypertension treated in primary care, patients with hypertension and/or type 2 diabetes were surveyed for cardiovascular disease risk factors and treatment 1992-1993. For reference, a random population sample from the same community was surveyed 1993-1994. LÄS MER

  3. 12. Common variants in genes regulating free fatty acid metabolism and risk of type 2 diabetes and cardiovascular disease

    Författare :Martin Carlsson; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cardiovascular disease; free fatty acids; genetics; UCP1; beta3-adrenergic receptor; beta2-adrenergic receptor; type 2 diabetes mellitus; FABP2; stroke; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Sammanfattning : Abstract The present study evaluated genetic and metabolic factors influencing the risk for type 2 diabetes and cardiovascular disease (CVD) with special reference to increased concentrations of free fatty acids (FFA) in 1174 Swedish diabetic and nondiabetic subjects. Common polymorphisms in the fatty acid binding protein 2 (FABP2), the B2-adrenergic receptor (B2-AR), the B3 -adrenergic receptor (B3-AR) and the uncoupling protein 1 (UCP-1) genes were related to anthropometric and metabolic variables. LÄS MER

  4. 13. Genetics of diabetic subtypes

    Författare :Camilla Cervin; Diabetes - klinisk obesitasforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocrinology; secreting systems; diabetology; Endokrinologi; Mutation; Association; Genetics; LADA; Diabetes; MODY; sekretion; diabetologi;

    Sammanfattning : There are two major types of diabetes mellitus, Type 1 Diabetes (T1D) and Type 2 Diabetes (T2D), however a number of subtypes have been defined and classified. Maternally Inherited Diabetes and Deafness (MIDD) and Maturity Onset Diabetes of the Young (MODY) are monogenic forms, whereas Latent Autoimmune Diabetes in Adults (LADA) is thought to be a polygenic subtype similar to T1D. LÄS MER

  5. 14. Antigen presenting cells in autoimmune diabetes: phenotype, function and modulation by Linomide

    Författare :Eva Dahlén; Lunds universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; secreting systems; Endocrinology; Linomide; costimulation; TNF-a; dendritic cells; Diabetes; macrophages; diabetology; Endokrinologi; sekretion; diabetologi; Immunology; serology; transplantation; Immunologi; serologi;

    Sammanfattning : The aim of this thesis was to better understand the role of antigen presenting cells (APC) in the development of diabetes in the nonobese diabetic (NOD) mouse. We have shown that DC and Mphi that infiltrate the islets of Langerhans produce tumour necrosis factor-a (TNF-a), a cytokine known to contribute to the pathogenesis in the early stages of diabetes development. LÄS MER

  7. 15. From the pancreatic beta cell to the endothelium:Pathophysiological aspects of Type 2 Diabetes

    Författare :Marloes Dekker Nitert; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sekretion; diabetologi; diabetology; insulin secretion; beta cells; glucose tolerance; insulin receptors; IGF-I receptors; endothelial cells; Endokrinologi; Type 2 Diabetes; secreting systems; Endocrinology;

    Sammanfattning : The incidence of Diabetes Mellitus increases globally in epidemic proportions. Type 2 Diabetes is the most prevalent form of Diabetes, comprising 90% of the patients. In Type 2 Diabetes, two processes contribute to the development of the disease: insufficient insulin secretion from the pancreatic ?-cell and insulin resistance of the target organs. LÄS MER