Sökning: "sLex"
Visar resultat 1 - 5 av 13 avhandlingar innehållade ordet sLex.
1. Synthetic analogs of sialyl Lewis x
Sammanfattning : The sialyl Lewis x (SLex) tetrasaccharide is the smallest recognizable ligand for selectins. The selectins constitute a vital part of the inflammatory cascade for recruitment of leukocytes to a site of tissue damage or microbial infection. LÄS MER
2. Helicobacter pylori : molecular mechanisms for variable adherence properties
Sammanfattning : More than half of all people worldwide are infected with H. pylori. The infection always cause a gastric inflammation that may develop into peptic ulcer disease or gastric cancer. Attachment proteins, adhesins, mediate specific adherence of H. LÄS MER
3. Herpesvirus-induced glycans: Selectin ligands and related structures on the surface of the infected cell
Sammanfattning : Human herpesviruses are usually acquired early in life and are widely distributed in the population. A common feature of all human herpesviruses is that they persist in the host after the primary infection. LÄS MER
4. Studies on the biosynthesis of ABH and Lewis epitopes on O-glycans
Sammanfattning : ABH and Lewis antigens are carbohydrate epitopes (glycans) found on a wide variety of cell surfaces. They are involved in many biological processes, e.g transplantation rejection, bacterial and viral adhesion, cell-cell communication and metastasis. The in vivo synthesis of glycans is mediated by glycosyltransferases (GTs). LÄS MER
5. Herpesvirus-induced expression of sLe(x) and related O-linked glycans in the infected cell
Sammanfattning : Lewis antigens constitute a family of fucosylated carbohydrate antigens (glycotopes), involved in leukocyte homing and related immunological phenomena. These glycotopes are only expressed restrictedly in normal cells, but are induced at appropriate occasions. It is well established that many tumors ?hijack? Lewis glycotopes for e.g. LÄS MER