Sökning: "ruthenium dipyridophenazine complex"

Hittade 3 avhandlingar innehållade orden ruthenium dipyridophenazine complex.

  1. 1. Polarized light spectroscopy studies of model membranes and DNA

    Författare :Maxim Kogan; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; emission; ruthenium dipyridophenazine complex; lipid bilayer; linear dichroism; membrane model; membrane orientation; bimolecular probe; DNA;

    Sammanfattning : Over the past decades Linear Dichroism (LD) spectroscopy has proven to be a powerful tool for studies of structure and functioning of different cell constituents, including DNA, cell membranes and proteins. Due to structural complexity of cell constituents, the LD studies of biomolecules depend on development of simplified model systems, which can mimic the original structure and functionality of the cell components. LÄS MER

  3. 2. Probing Biomolecules and Membranes using Spectroscopy and Microscopy

    Författare :Frida Svensson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ruthenium dipyridophenazine complex; biomolecular probes; microscopy; membrane; tryptophan; retinoic acid; peptide-lipid interaction; Linear dichroism; emission; lifetime imaging;

    Sammanfattning : .... LÄS MER

  4. 3. Aspects of Antisense and Antigene Chemistry of Oligonucleotides Tethered to Intercalators

    Författare :Dimitri Ossipov; Jesper Wengel; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bioorganic chemistry; oligonucleotides; intercalators; ruthenium complexes; RNase H cleavage; photocross-linkage; Bioorganisk kemi; Bioorganic chemistry; Bioorganisk kemi; bioorganisk kemi; Biorganic Chemistry;

    Sammanfattning : Synthetic and physicochemical studies on appropriately functionalized ODN-conjugates have been performed to evaluate their abilities to act as antisense agents against RNA or as intramolecular DNA cross-linking agents. Intercalating aromatic systems [phenazine (Pnz), dipyridophenazine (DPPZ)] and metallointercalators such as Ru2+(phen)2(DPPZ) and Ru2+(tpy)(DPPZ)L [where L = chemically or photochemically labile ligand, phen = phenanthroline, tpy = terpyridine], which are covalently tethered to the oligo-deoxynucleotides (ODNs), have been chosen for this purpose. LÄS MER