Sökning: "replication complex"
Visar resultat 1 - 5 av 145 avhandlingar innehållade orden replication complex.
1. Genetics of complex disease
Sammanfattning : To find true genetic associations in complex diseases, such as allergic rhinitis and chronic rhinosinusitis, is a difficult task. Both are polygenetic diseases where it is believed that genetic variation in several genes make up their phenotypes. LÄS MER
2. Molecular characterization of the Tick-borne encephalitis virus : Environments and replication
Sammanfattning : The flavivirus genus is of major concern for world morbidity and mortality and includes viruses causing both encephalitic as well as hemorrhagic diseases. The incidence of Tick-borne encephalitis is increasing in many European countries and several reports have emphasized the expansion of the main vector, Ixodes ricinus. LÄS MER
3. Complex disease genetics : Utilising targeted sequencing and homogeneous ancestry
Sammanfattning : The complex disease investigations presented in this thesis aimed to provide new information regarding underlying genetics by using targeted sequencing and ethnically homogeneous cohorts. This work moved past current methodologies and addressed data stratification issues, that might have been hindering new findings. LÄS MER
4. The Smc5/6 complex : linking DNA replication with chromosome segregation
Sammanfattning : In order to faithfully propagate the genetic material from one generation to the next, cells need to properly replicate and segregate their chromosomes. The three well-conserved eukaryotic Structural Maintenance of Chromosomes (SMC) protein complexes, cohesin, condensin and the Smc5/6 complex (Smc5/6) organize chromosomes to ensure that the daughter cells receive a full complement of chromosomes. LÄS MER
5. Polymer Microoptics in Silicon Micromachining
Sammanfattning : MEMS (micro-electro-mechanical system) technology is an established field, which makes use of the advanced state of silicon processing to fabricate complex electro-mechanical structures and devices. Microoptics is a new, but advanced technology within the field of optics. LÄS MER