Sökning: "recombinant hemoglobin"

Visar resultat 1 - 5 av 14 avhandlingar innehållade orden recombinant hemoglobin.

  1. 1. Human Fetal Hemoglobin : Biochemical Characterization and Recombinant Production

    Författare :Khuanpiroon Ratanasopa; Tillämpad biokemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Blood substitutes; HBOCs; HbF; recombinant hemoglobin; pseudoperoxidase; ITC; haptoglobin;

    Sammanfattning : Blood transfusion is a common medical procedure when oxygen supply in the body is impaired. However, blood transfusion is not always without risks. The uncontrolled spreading of blood borne pathogens such as HIV or hepatitis B and C virus has urged researchers to look for “blood substitutes”. LÄS MER

  3. 2. Engineering of Human Fetal Hemoglobin

    Författare :Karin Kettisen; Tillämpad biokemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; fetal hemoglobin; protein engineering; recombinant protein production; protein purification; chromatography; oxygen carrier; redox reactions; net surface charge; DNA cleavage;

    Sammanfattning : In blood, the oxygen-transporting protein hemoglobin (Hb) governs the oxygenation of cells and tissues. Naturally, this protein has claimed a place in the center of the research field of artificial oxygen therapeutics. LÄS MER

  4. 3. Biochemical and Physiological Characterization of Nonsymbiotic Plant Hemoglobins

    Författare :Nélida Leiva; Tillämpad biokemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hemoglobin; Non-symbiotic hemoglobin; Sugar beet; Ligand binding; Nitric oxide; Gene expression; Gene overexpression; Poplar; Arabidopsis; Lepidium campestre.;

    Sammanfattning : Hemoglobins (Hb) are usually associated with blood in humans. However, these proteins are widely distributed among living organisms. In plants the most known group are the leghemoglobins. Still, other Hbs that not participate in symbiosis are also found. LÄS MER

  5. 4. Vitreoscilla hemoglobin. In vitro mutagenesis and transcript profiling to improve its biotechnological usefulness

    Författare :Charlotte Andersson; Tillämpad biokemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemical technology; Biokemisk teknik; gene expression analysis; transcript profiling; microarray; DNA chips; microaerobic; hypoxia; oxygen-limited; bacterial hemoglobin; Escherichia coli; Vitreoscilla hemoglobin VHb ;

    Sammanfattning : Vitreoscilla is an obligate aerobic bacterium found in oxygen-poor environments such as stagnant ponds and decaying vegetable matter. Vitreoscilla induces the production of a homodimeric hemoglobin (VHb) when subjected to oxygen-limiting conditions. LÄS MER

  7. 5. Alpha-1-microglobulin, heme-binding protein, reductase and antioxidant

    Författare :Maria Allhorn; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reduction; inflammation; chronic ulcers; collagen; low density lipoproteins; Medicin människa och djur ; Medicine human and vertebrates ; antioxidation; heme; hemoglobin; alpha-1-microglobulin; lipocalin;

    Sammanfattning : This thesis describes structural and functional studies of alpha-1-microglobulin (a1m), a 26 kDa plasma and tissue protein that is evolutionarily well-conserved and belongs to the lipocalin superfamily. The lipocalins are polypeptides of 160-190-amino acids that are folded into an 8-stranded beta-barrel forming a pocket with a hydrophobic interior. LÄS MER