Sökning: "rat strains"

Visar resultat 1 - 5 av 98 avhandlingar innehållade orden rat strains.

  1. 1. Deviant sexual behavior, hormones and sex-chromosomal relationship : A study in the spontaneously hypertensive rat (SHR)

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Anders Wall; Uppsala universitet.; [1997]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; SHR; WKY; Rat; Copulatory performance; Deviant sexual behavior; Neuroendocrine mechanisms; Neonatal; Farmakologi; MEDICINE Physiology and pharmacology Pharmacological research; MEDICIN Fysiologi och farmakologi Farmakologisk forskning; Neurology; neurologi;

    Sammanfattning : The general aim of the present thesis was to gain insight into some biological factors that influencedeviant sexual performance. Two inbred strains selectively bred (hypertension) from the same Wistarrat colony were used: the spontaneously hypertensive rat (SHR) and its normotensive progenitor theWistar Kyoto rat (WKY). LÄS MER

  3. 2. Development and Evaluation of Web Applications for Investigating Candidate Genes in Rat Models of Complex Diseases

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Lars Andersson; Göteborgs universitet.; Gothenburg University.; [2008]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; rat; complex disease; rheumatoid arthritis; type 2 diabetes mellitus; QTL; candidate genes; web application; text mining;

    Sammanfattning : Many human diseases, such as rheumatoid arthritis and type 2 diabetes mellitus, have a very complex development, depending on both environmental and multiple genetic factors. By crossing inbred rat strains susceptible to a genetic disorder with strains resistant to the same disorder, genomic regions associated with the disease can be identified, so called quantitative trait loci (QTLs). LÄS MER

  4. 3. Inflammation in Parkinson’s Disease and Experimental Neural Transplantation. Role of Cellular Responses, Cytokines and Immunosuppression in Graft Rejection

    Detta är en avhandling från Bilal Mirza, Section for Neuronal Survival, BMC-A10, SE-221 84 Lund, Sweden

    Författare :Bilal Mirza; Lunds universitet.; Lund University.; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; graft rejection.; pig; human; rat; xenogeneic; allogeneic; syngeneic; transplantation immunology; immunosuppression; cytokines; neural transplantation; Parkinson’s Disease; inflammation; neurodegeneration; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Sammanfattning : Abstract: Parkinson’s disease (PD) is a common neurodegenerative disorder. There is no proven protection, but many treatments can partially improve symptoms. The disease is caused by monogenetic mechanisms in very few cases, but for the majority of patients the etiology is unknown. LÄS MER

  5. 4. Experimental and Clinical Studies of Oxidative Stress in Pre-Eclampsia

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Peppi Nash; Uppsala universitet.; [2007]
    Nyckelord :Obstetrics and gynaecology; Pre-eclampsia; Oxidative stress; Diabetes; Placenta; Rat; Antioxidants; Suramin; Vitamin E; Vitamin C; PAI-1; PAI-2; Obstetrik och kvinnosjukdomar;

    Sammanfattning : Impaired placentation and oxidative stress are proposed to play major roles in the pathogenesis of pre-eclampsia (PE). It has recently been pointed out that PE might be more than one disease and may have several different pathogeneses. LÄS MER

  7. 5. Oxidative stress, antioxidative defence and outcome of gestation in experimental diabetic pregnancy

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Jonas Cederberg; Uppsala universitet.; [2001]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Diabetes; pregnancy; rat; ROS; free oxygen radicals; TBARS; isoprostanes; protein carbonyls; embryo; vitamin C; vitamin E; Cellbiologi; MEDICINE Morphology; cell biology; pathology Cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Sammanfattning : Maternal type 1 diabetes is associated with an increased risk for foetal malformations. The mechanism by which diabetes is teratogenic is not fully known. Previous studies have demonstrated that radical oxygen species can contribute to the teratogenicity of glucose and diabetes. LÄS MER