Sökning: "quantification"

Visar resultat 21 - 25 av 1090 avhandlingar innehållade ordet quantification.

1. 21. Multiplexed absolute quantification of blood plasma proteins using targeted proteomics

   Författare :David Kotol; Mathias Uhlén; Edfors Fredrik; Roman Zubarev; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mass spectrometry; targeted proteomics; stable isotope standards; recombinant protein standards; absolute quantification; blood plasma; multiplex analysis; plasma profiling; Biotechnology; Bioteknologi;

   Sammanfattning : Proteins are the molecular building blocks of all living organisms. They are the functioning actors in metabolism and communication, and they give specific architecture and purpose to all tissues. Their abundance is dynamic and can be interpreted and associated to different physiological states or diseases. LÄS MER

3. 22. Process-induced disorder of pharmaceutical materials : Mechanisms and quantification of disorder

   Författare :Samaneh Pazesh; Göran Alderborn; Jonas Berggren; Niklas Sandler; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Milling; Comminution; Powder flow; Amorphisation; Raman spectroscopy; Atomic force microscopy; Plastic stiffness; Elastic stiffness; Pharmaceutical Science; Farmaceutisk vetenskap;

   Sammanfattning : One of the most important prerequisites in the drug development is to attain a reproducible and robust product in terms of its nature, and its chemical and physical properties. This can be challenging, since the crystalline form of drugs and excipients can be directly transformed into the amorphous one during normal pharmaceutical processing, referred to as process-induced amorphisation or process-induced disorder. LÄS MER

4. 23. Towards Clinical Implementation of Dynamic Positron Emission Tomography in Neurodegenerative Diseases

   Författare :My Jonasson; Mark Lubberink; Lieuwe Appel; Jens Sörensen; Michel Koole; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Positron emission tomography; PET; Molecular imaging; Quantification; Kinetic modelling; Parametric images; Alzheimer’s disease; Parkinson’s disease; Radiology; Radiologi;

   Sammanfattning : Alzheimer’s disease (AD) and Parkinson’s disease (PD) are the two most common neurodegenerative disorders worldwide. Positron emission tomography (PET), together with suitable biomarkers, can aid in the clin-ical evaluation as well as in research investigations of these diseases. LÄS MER

5. 24. Assessment of attenuation correction methods for quantitative neuro-PET/MR

   Författare :Joao M. Sousa; Mark Lubberink; Lieuwe Appel; Håkan Ahlström; Mathias Engström; Ivo Rausch; Radiologi Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PET; MRI; attenuation correction; 68Ge transmission; quantification; 11C-PE2I; MRAC; DAT; CBF; Medicinsk radiofysik; Medical Radiophysics;

   Sammanfattning : Hybrid PET/magnetic resonance (MR) can provide physiological, functional, and structural information simultaneously, facilitating research in neurological disorders. For quantitative PET, correction for photon attenuation (AC) is necessary. LÄS MER

7. 25. Konzeptuelle Struktur und materielle Manifestation : Nominale Part-Whole-Konstruktionen aus einer typologischen Perspektive

   Författare :Daniel Ormelius; Tyska; []
   Nyckelord :HUMANIORA; HUMANITIES; typological patterns; spatial representations; conceptual structures; morphosyntactic structures; ‘part-whole’ constructions; boundedness; internal structure; quantification; referentiality; quantifier phrase; noun phrase; determiner phrase; German language and literatur; Tyska språk och litteratur ;

   Sammanfattning : The aim of this thesis is to investigate the relation between intrasubjective mental representations – ‘conceptual structures’ – and their intersubjectively available material manifestation, in particular morphosyntactic representations. Such an investigation presupposes the analysis of not only extralinguistically established modules but also of structural levels that are inherent components of the language system. LÄS MER