Sökning: "quantification"

Visar resultat 16 - 20 av 1090 avhandlingar innehållade ordet quantification.

1. 16. Single Molecule Detection : Microfluidic Automation and Digital Quantification

   Författare :Malte Kühnemund; Mats Nilsson; Ulf Landegren; Sten Linnarsson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; single molecule; digital; rolling circle amplification; magnetic particle; padlock probe; microfluidics; resistive pulse sensing; lab on chip; mobile phone microscopy; enrichment; sequencing;

   Sammanfattning : Much of recent progress in medical research and diagnostics has been enabled through the advances in molecular analysis technologies, which now permit the detection and analysis of single molecules with high sensitivity and specificity. Assay sensitivity is fundamentally limited by the efficiency of the detection method used for read-out. LÄS MER

3. 17. High-throughput protein analysis using mass spectrometry-based methods

   Författare :Tove Boström; Sophia Hober; Thomas Laurell; Ole N. Jensen; KTH; []
   Nyckelord :Proteomics; mass spectrometry; affinity proteomics; immunoenrichment; immunoprecipitation; IMAC; screening; protein production; protein purification; ISET; quantification; SILAC; stable isotope standard; antibody validation; Bioteknologi; Biotechnology;

   Sammanfattning : In the field of proteomics, proteins are analyzed and quantified in high numbers. Protein analysis is of great importance and can for example generate information regarding protein function and involvement in disease. Different strategies for protein analysis and quan- tification have emerged, suitable for different applications. LÄS MER

4. 18. On posterior capsule opacification

   Författare :Karin Sundelin; Göteborgs universitet; []
   Nyckelord :posterior capsule opacification; quantification; capsulotomy; benefit; intraocular; lens; optic design; Catquest; Evaluation of Posterior Capsule Opacification;

   Sammanfattning : AimsPosterior capsule opacification (PCO) is the most common complication after cataractsurgery. The aim of this study was to increase our knowledge about PCO regardingquantification, treatment effects and how different designs of intraocular lenses(IOLs) influence occurrence. LÄS MER

5. 19. Mitochondrial DNA in Sensitive Forensic Analysis

   Författare :Martina Nilsson; Marie Allen; Ulf Gyllensten; Antti Sajantila; Uppsala universitet; []
   Nyckelord :Genetics; Forensic genetics; Mitochondrial DNA; HVI HVII; Nuclear DNA; Quantification; Real-time PCR; Immobilised SSO probe assay; Pyrosequencing; Discrimination power; Coding region; Mixtures; Genetik;

   Sammanfattning : Genetic profiling is commonly performed on the autosomes using multiple DNA markers. Although routine forensic DNA analysis is robust and based on reliable technologies, samples with degraded or limited amounts of DNA often fail. In these cases, the analysis of mitochondrial DNA (mtDNA) can be very valuable due to the high copy number per cell. LÄS MER

7. 20. Quantitative immunochemistry in tissue sections : With special reference to urinary bladder carcinoma

   Författare :Kenneth Wester; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Urinary bladder carcinoma; immunohistochemistry; quantification; image analysis; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

   Sammanfattning : Urinary bladder carcinoma affects about 2 000 people in Sweden every year. It is a heterogeneous disease and for adequate treatment decisions, prognostic tools are needed. Many of these are based on immunohistochemistry (MC) and hampered by poorly reproducible methodologies and subjective evaluations. LÄS MER